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1-Minute Consult

Is the MTHFR gene mutation associated with thrombosis?

Andrew Dhawan, MD, DPhil and Charis Eng, MD, PhD
Cleveland Clinic Journal of Medicine November 2023, 90 (11) 661-663; DOI: https://doi.org/10.3949/ccjm.90a.23044
Andrew Dhawan
Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; Center for Personalized Genetic Healthcare, Medical Specialties Institute, Cleveland Clinic, Cleveland, OH
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Charis Eng
Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; Center for Personalized Genetic Healthcare, Medical Specialties Institute, Cleveland Clinic, Cleveland, OH; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH; Professor of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Article Information

vol. 90 no. 11 661-663
DOI 
https://doi.org/10.3949/ccjm.90a.23044
PubMed 
37914198

Published By 
Cleveland Clinic Journal of Medicine
Print ISSN 
0891-1150
Online ISSN 
1939-2869
History 
  • Published online November 1, 2023.

Copyright & Usage 
Copyright © 2023 The Cleveland Clinic Foundation. All Rights Reserved.

Author Information

  1. Andrew Dhawan, MD, DPhil
  1. Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; Center for Personalized Genetic Healthcare, Medical Specialties Institute, Cleveland Clinic, Cleveland, OH
  1. Charis Eng, MD, PhD⇑
  1. Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH; Center for Personalized Genetic Healthcare, Medical Specialties Institute, Cleveland Clinic, Cleveland, OH; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH; Professor of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. Address:
    Charis Eng, MD, PhD, Director, Center for Personalized Genetic Healthcare, NE50, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; engc{at}ccf.org
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Cleveland Clinic Journal of Medicine: 90 (11)
Cleveland Clinic Journal of Medicine
Vol. 90, Issue 11
1 Nov 2023
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Is the MTHFR gene mutation associated with thrombosis?
Andrew Dhawan, Charis Eng
Cleveland Clinic Journal of Medicine Nov 2023, 90 (11) 661-663; DOI: 10.3949/ccjm.90a.23044

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Is the MTHFR gene mutation associated with thrombosis?
Andrew Dhawan, Charis Eng
Cleveland Clinic Journal of Medicine Nov 2023, 90 (11) 661-663; DOI: 10.3949/ccjm.90a.23044
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  • Article
    • BACKGROUND
    • WHAT IS A SINGLE NUCLEOTIDE POLYMORPHISM?
    • HOW COMMON IN THE GENERAL POPULATION?
    • RISK OF THROMBOSIS AND MTHFR VARIANTS
    • SHOULD PATIENTS BE TESTED FOR MTHFR VARIANTS?
    • TEST INTERPRETATION
    • MANAGEMENT
    • THE BOTTOM LINE
    • DISCLOSURES
    • Acknowledgments
    • REFERENCES
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  • PDF

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