Hematology

  • Modifying genetic diseases: Promises to be realized?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine January 2020, 87 (1) 7-8; DOI: https://doi.org/10.3949/ccjm.87b.01020

    Genetic engineering offers hope to patients and families who previously had little.

  • Atraumatic splenic rupture in acute myeloid leukemia
    Karthik Gnanapandithan, MD, MS
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 715-716; DOI: https://doi.org/10.3949/ccjm.86a.19042

    Atraumatic splenic rupture is rare but potentially life-threatening, especially if the diagnosis is delayed.

  • A complication of enoxaparin injection
    Ahmad Muneer Sharayah, MD, Samrah Zaigham, MD, Noor Hajjaj, MD and Mihir Maniar, DO
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 648-649; DOI: https://doi.org/10.3949/ccjm.86a.19026

    Computed tomography revealed a hematoma measuring 15 by 15 cm compressing the bladder and causing hydronephrosis.

  • An unusual cause of bruising
    Tahani Atieh, DO and Alan Lichtin, MD
    Cleveland Clinic Journal of Medicine August 2019, 86 (8) 535-542; DOI: https://doi.org/10.3949/ccjm.86a.18119

    The coagulation assay, particularly the prothrombin time and aPTT, is key in initially assessing a bleeding abnormality.

  • A 69-year-old woman with double vision and lower-extremity weakness
    Ibrahim Migdady, MD, Maryann Mays, MD and Kerry H. Levin, MD
    Cleveland Clinic Journal of Medicine June 2019, 86 (6) 374-379; DOI: https://doi.org/10.3949/ccjm.86a.18113

    The onset was sudden, and the symptoms were gradually getting worse.

  • Anti-Xa assays: What is their role today in antithrombotic therapy?
    Erika Hutt Centeno, MD, Michael Militello, PharmD, RPH, BCPS and Marcelo P. Gomes, MD
    Cleveland Clinic Journal of Medicine June 2019, 86 (6) 417-425; DOI: https://doi.org/10.3949/ccjm.86a.18029

    Should clinicians abandon the aPTT for monitoring heparin therapy in favor of anti-Xa assays?

  • The tests that we order define us
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2019, 86 (3) 150; DOI: https://doi.org/10.3949/ccjm.86b.03019

    In practice we balance the inputs from Watson, “Dr. Google,” our experience, and the specific data from the patient.

  • Three neglected numbers in the CBC: The RDW, MPV, and NRBC count
    Jori E. May, MD, Marisa B. Marques, MD, Vishnu V.B. Reddy, MD and Radhika Gangaraju, MD
    Cleveland Clinic Journal of Medicine March 2019, 86 (3) 167-172; DOI: https://doi.org/10.3949/ccjm.86a.18072

    These values have diagnostic utility and potential prognostic significance.

  • Aleukemic leukemia cutis
    Tuyet Nguyen Abraham, MD, MSC, Peter Morawiecki, MD, Amy Flischel, MD and Bharata Agrawal, MD
    Cleveland Clinic Journal of Medicine February 2019, 86 (2) 85-86; DOI: https://doi.org/10.3949/ccjm.86a.18057

    An 85-year-old man presented with rapidly progressive nodules on the scalp, neck, trunk, and extremities.

  • Monoclonal gammopathy of undetermined significance: A primary care guide
    Monoclonal gammopathy of undetermined significance: A primary care guide
    Jack Khouri, MD, Christy Samaras, DO, Jason Valent, MD, Alex Mejia Garcia, MD, Beth Faiman, PhD, CNP, Saveta Mathur, CNP, Kim Hamilton, CNP, Megan Nakashima, MD and Matt Kalaycio, MD
    Cleveland Clinic Journal of Medicine January 2019, 86 (1) 39-46; DOI: https://doi.org/10.3949/ccjm.86a.17133

    Low-risk MGUS may not require subspecialty referral and can be followed by the outpatient provider.

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