Genetics

  • Pregnancy in a woman with congenitally corrected transposition of the great arteries
    Pregnancy in a woman with congenitally corrected transposition of the great arteries
    Sarah A. Goldstein, MD, Lisa Sorenson, CNP, Jeffrey B. Chapa, MD and Richard A. Krasuski, MD
    Cleveland Clinic Journal of Medicine April 2021, 88 (4) 228-236; DOI: https://doi.org/10.3949/ccjm.88a.20136

    She presents with nausea and emesis 7 weeks after her last menstrual period.

  • Male and female pattern hair loss: Treatable and worth treating
    Nina L. Tamashunas, BS and Wilma F. Bergfeld, MD, FAAD
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 173-182; DOI: https://doi.org/10.3949/ccjm.88a.20014

    Early recognition and treatment can help preserve as much hair as possible.

  • Cardiac surveillance for anti-HER2 chemotherapy
    Patrick Collier, MD, PhD, FASE, FESC, FACC, Muzna Hussain, MD, Zoran B. Popovic, MD, PhD and Brian P. Griffin, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 110-116; DOI: https://doi.org/10.3949/ccjm.88a.19150

    A more focused approach is advocated.

  • Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    CME article
    Tristan Lee, MD, Jeffrey M. Clarke, MD, Deepali Jain, MD, Sendhilnathan Ramalingam, MD and Vishal Vashistha, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 117-127; DOI: https://doi.org/10.3949/ccjm.88a.19148

    Targeted therapy has revolutionized treatment of patients with advanced solid tumors.

  • A 21-year-old woman with Ehlers-Danlos syndrome and persistent lightheadedness
    Raed Qarajeh, MD, Laith A. Derbas, MD, Mouin Abdallah, MD, MSc and Faraz Kureshi, MD, MSc
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 93-97; DOI: https://doi.org/10.3949/ccjm.88a.19137

    She has a long history of lightheadedness upon standing, and it is getting worse.

  • Trying to get ahead of Alzheimer disease
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 517-518; DOI: https://doi.org/10.3949/ccjm.87b.09020

    Sorting out patients destined to have Alzheimer disease remains a challenge.

  • Thoracic aortic aneurysm: Optimal surveillance and treatment
    CME article
    Tom Kai Ming Wang, MBCHB, MD(res), FRACP and Milind Y. Desai, MD
    Cleveland Clinic Journal of Medicine September 2020, 87 (9) 557-568; DOI: https://doi.org/10.3949/ccjm.87a.19140-1

    Early detection, surveillance, and treatment are critical.

  • Does a short QT interval increase the risk of cardiac death in healthy people?
    Ahmed Subahi, MD, Ahmed S. Yassin, MD, Oluwole Adegbala, MD, Mohamed Shokr, MD and Luis Afonso, MD
    Cleveland Clinic Journal of Medicine July 2020, 87 (7) 398-400; DOI: https://doi.org/10.3949/ccjm.87a.19090

    No, but it may warrant further investigation to determine if the patient is at risk.

  • Familial hypercholesterolemia: Clarifications
    Taher Modarressi, MD
    Cleveland Clinic Journal of Medicine June 2020, 87 (6) 320; DOI: https://doi.org/10.3949/ccjm.87c.06001

    Comments on xanthoma vs xanthelasmas, and goal LDL-C.

  • In Reply: Familial hypercholesterolemia: Clarifications
    Nishant P. Shah, MD,FACC, Haitham M. Ahmed, MD and W. H. Wilson Tang, MD
    Cleveland Clinic Journal of Medicine June 2020, 87 (6) 320; DOI: https://doi.org/10.3949/ccjm.87c.06002

    The authors' response.

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