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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Genetics

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    Altered mental status in a man with metabolic syndrome
    Bernie P. Wu, BS, Molly Wheeler, PharmD, Jennifer K. Hockings, PharmD, PhD, Andrew Coulter, MD and Leopoldo Pozuelo, MD
    Cleveland Clinic Journal of Medicine August 2022, 89 (8) 445-450; DOI: https://doi.org/10.3949/ccjm.89a.21050

    A 25-year-old man with bipolar I disorder, hypertension, posttraumatic stress disorder, and obesity was found unresponsive with shallow breathing and foaming at the mouth.

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    Spotty skin pigmentation in Carney complex
    Azusa Sano, MD, Yosuke Ono, MD, PhD, Naoya Fujita, MD and Yuji Tanaka, MD, PhD
    Cleveland Clinic Journal of Medicine June 2022, 89 (6) 307-308; DOI: https://doi.org/10.3949/ccjm.89a.21069

    Characteristic skin findings and their locations can indicate underlying hereditary lentiginosis syndromes.

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    Breast cancer risk evaluation for the primary care physician
    Christine L. Klassen, MD, Elizabeth Gilman, MD, Aparna Kaur, MD, Sara P. Lester, MD and Sandhya Pruthi, MD
    Cleveland Clinic Journal of Medicine March 2022, 89 (3) 139-146; DOI: https://doi.org/10.3949/ccjm.89a.21023

    The authors offer a systematic approach to the assessment and management of patients at risk of breast cancer.

  • You have access
    Rapid cognitive decline and myoclonus in a 52-year-old woman
    William Gravley, MS, Caleb Murphy, MD, MBA, Chia-Dan Kang, MD and Badrunnisa Hanif, MD
    Cleveland Clinic Journal of Medicine October 2021, 88 (10) 572-583; DOI: https://doi.org/10.3949/ccjm.88a.20004

    Symptoms also included confusion, blank staring, blurred vision, incoordination of the extremities, decreased verbal communication, and holding her left hand in a fist.

  • You have access
    Tuberous sclerosis complex
    Jesica Martín Carmona, MD, Elisabeth Gómez Moyano, MD, PhD, Ana Raquel de Castro Almeida, MD and Leandro Martínez Pilar, MD, PhD
    Cleveland Clinic Journal of Medicine July 2021, 88 (7) 367-368; DOI: https://doi.org/10.3949/ccjm.88a.20075

    A rare disorder caused by mutations of tumor-suppressor genes.

  • Pregnancy in a woman with congenitally corrected transposition of the great arteries
    You have access
    Pregnancy in a woman with congenitally corrected transposition of the great arteries
    Sarah A. Goldstein, MD, Lisa Sorenson, CNP, Jeffrey B. Chapa, MD and Richard A. Krasuski, MD
    Cleveland Clinic Journal of Medicine April 2021, 88 (4) 228-236; DOI: https://doi.org/10.3949/ccjm.88a.20136

    She presents with nausea and emesis 7 weeks after her last menstrual period.

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    Male and female pattern hair loss: Treatable and worth treating
    Nina L. Tamashunas, BS and Wilma F. Bergfeld, MD, FAAD
    Cleveland Clinic Journal of Medicine March 2021, 88 (3) 173-182; DOI: https://doi.org/10.3949/ccjm.88a.20014

    Early recognition and treatment can help preserve as much hair as possible.

  • You have access
    Cardiac surveillance for anti-HER2 chemotherapy
    Patrick Collier, MD, PhD, FASE, FESC, FACC, Muzna Hussain, MD, Zoran B. Popovic, MD, PhD and Brian P. Griffin, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 110-116; DOI: https://doi.org/10.3949/ccjm.88a.19150

    A more focused approach is advocated.

  • Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    You have access
    Precision treatment for metastatic non–small cell lung cancer: A conceptual overview
    Tristan Lee, MD, Jeffrey M. Clarke, MD, Deepali Jain, MD, Sendhilnathan Ramalingam, MD and Vishal Vashistha, MD
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 117-127; DOI: https://doi.org/10.3949/ccjm.88a.19148

    Targeted therapy has revolutionized treatment of patients with advanced solid tumors.

  • You have access
    A 21-year-old woman with Ehlers-Danlos syndrome and persistent lightheadedness
    Raed Qarajeh, MD, Laith A. Derbas, MD, Mouin Abdallah, MD, MSc and Faraz Kureshi, MD, MSc
    Cleveland Clinic Journal of Medicine February 2021, 88 (2) 93-97; DOI: https://doi.org/10.3949/ccjm.88a.19137

    She has a long history of lightheadedness upon standing, and it is getting worse.

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