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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Vascular Medicine

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    Should I start anticoagulation in my patient newly diagnosed with pulmonary hypertension?
    Tark Abou-Elmagd, MD, MSc, MBBCh and Shraddha Narechania, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 339-343; DOI: https://doi.org/10.3949/ccjm.92a.24083

    The decision hinges on the subtype of pulmonary hypertension the patient has.

  • You have access
    Nitrogen: The unsung hero of vascular physiology
    Adam J. Brown, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 344-346; DOI: https://doi.org/10.3949/ccjm.92a.24120

    The seventh element on the periodic table—nitrogen—may not come to mind often in day-to-day medical practice, but it is more exciting than you might think.

  • You have access
    Direct oral anticoagulants: Challenging prescribing scenarios in everyday practice
    CME article
    Syed Bukhari, MD, MHA, Mohamed Ghoweba, MD, Syed Zamrak Khan, MD, Ammar Saati, MD and Marcelo Gomes, MD
    Cleveland Clinic Journal of Medicine June 2025, 92 (6) 353-361; DOI: https://doi.org/10.3949/ccjm.92a.24061

    Preapproval trials of direct oral anticoagulants excluded patients with extreme body weight and advanced kidney and liver disease and those who had undergone bariatric surgery. Cautious decision-making in these patients is warranted.

  • Managing right ventricular failure in the setting of pulmonary embolism
    You have access
    Managing right ventricular failure in the setting of pulmonary embolism
    Sharmeen Sorathia, MD, Anibelky Almanzar, MD, Abhishek Bhandiwad, MD and Phoo Pwint Nandar, MD
    Cleveland Clinic Journal of Medicine May 2025, 92 (5) 301-309; DOI: https://doi.org/10.3949/ccjm.92a.24069

    The authors review current management strategies, including medical, percutaneous interventional, and surgical options, and discuss recent advances in the field.

  • You have access
    Prolonged venous filling time and dependent rubor in a patient with peripheral artery disease
    Scott L. Hagan, MD and Jeffrey W. Redinger, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 205-206; DOI: https://doi.org/10.3949/ccjm.92a.24056

    Physical examination in a man who presented with foot pain revealed absent bilateral posterior tibial and dorsalis pedis pulses and dusky erythema of both feet.

  • A man with chronic limb-threatening ischemia and no revascularization options: Can we save his foot?
    You have access
    A man with chronic limb-threatening ischemia and no revascularization options: Can we save his foot?
    Fachreza Aryo Damara, MD, Khaled I. Alnahhal, MD, Hassan Dehaini, MD, Georgeanne Botek, DPM, Ammar A. Saati, MD, Pulkit Chaudhury, MD and Lee Kirksey, MD, MBA
    Cleveland Clinic Journal of Medicine November 2024, 91 (11) 683-692; DOI: https://doi.org/10.3949/ccjm.91a.23077

    The patient’s right foot was edematous with extensive, dry-appearing gangrene of the big toe, and no pedal pulses were felt.

  • You have access
    Abdominal pain in a patient with epistaxis, telangiectasias, and arteriovenous malformations
    Akash Mathavan, MD, Akshay Mathavan, MD, Andreas Giovanni Zori, MD, Marc Stuart Zumberg, MD, Jeb M. Justice, MD and Ali Ataya, MD
    Cleveland Clinic Journal of Medicine October 2024, 91 (10) 601-608; DOI: https://doi.org/10.3949/ccjm.91a.24042

    The pain was radiating to the back, exacerbated by eating, and accompanied by intermittent nausea and fatigue.

  • You have access
    Should every patient with an unprovoked venous thromboembolism have a hypercoagulable workup?
    Jaime Tan, MD, Neeladri Misra, MD and Sivakumar Reddy, MD
    Cleveland Clinic Journal of Medicine September 2024, 91 (9) 531-533; DOI: https://doi.org/10.3949/ccjm.91a.24016

    In the absence of consensus guidelines addressing this question, an individualized approach that considers personal and family history is needed.

  • You have access
    Stop the clot: When is laboratory evaluation for thrombophilia warranted?
    Jaideep Singh Bhalla, MD, G. Jay Bishop, MD and Scott J. Cameron, MD, PhD
    Cleveland Clinic Journal of Medicine September 2024, 91 (9) 535-536; DOI: https://doi.org/10.3949/ccjm.91a.24058

    Evidence does not support routine testing for an underlying hereditary thrombophilia after an arterial or venous thrombosis. Instead, the benefits of testing must be discussed with each patient.

  • You have access
    Mesenteric ischemia: Recognizing an uncommon disorder and distinguishing among its causes
    Teresa Wu, MD and Aravinda Nanjundappa, MBBS, MD
    Cleveland Clinic Journal of Medicine September 2024, 91 (9) 545-550; DOI: https://doi.org/10.3949/ccjm.91a.23094

    Mesenteric ischemia is associated with high mortality and often poses a diagnostic challenge. Early recognition and diagnosis are imperative to improve outcomes.

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