Table of Contents
Medical Grand Rounds
- Angioedema: Frightening and frustrating
The dramatic swelling of angioedema develops in minutes to hours. Often, no cause is apparent.
1-Minute Consult
- Should methotrexate be a first-line treatment for rheumatoid arthritis?
The evidence is in: Methotrexate is safe and effective as a first-line treatment for rheumatoid arthritis for many patients.
- Should all diabetic patients take ACE inhibitors, even those without proteinuria?
To give ACE inhibitors to all diabetic patients would be premature, but these agents have clear indications in some patients.
Review
- Management of perimenopause: Focus on alternative therapies
What unregulated over-the-counter products are your patients taking? What do these products do?
- Diagnosis and treatment of glucocorticoid-induced osteoporosis
Nearly everyone loses bone mass when they take corticosteroids long-term. Physicians should take proactive steps to mitigate the problem.
- Diagnosing and treating plantar fasciitis: A conservative approach to plantar heel pain
A simple diagnostic and treatment strategy that emphasizes nonsurgical treatment for this frustrating condition.
Current Drug Therapy
- Hypersensitivity syndrome to antiepileptic drugs: A review including new anticonvulsants
How to recognize this potentially fatal adverse reaction and choose a safe substitute drug.
Interpreting Key Trials
- United Kingdom Prospective Diabetes Study (UKPDS)
A 20-year study shows that intensive hlood glucose control is beneficial in type 2 diabetes.