Table of Contents
From the Editor
- The Vioxx withdrawal: Latest in the COX-2 controversies
Discussion of the COX-2 inhibitors has been emotionally polarized every step of the way, and it’s not over. Two other COX-2 drugs are still available, and much money is at stake.
Review
Benign prostatic hyperplasia: Now we can begin to tailor treatmentThe management of benign prostatic hyperplasia has improved considerably in recent years. A review of medications, surgery, and new minimally invasive procedures.
Heart Valve Update
- Understanding valvular heart disease in patients with systemic autoimmune diseases
Specific systemic autoimmune diseases are associated with distinct valvular heart disorders. Earlier detection and management may prevent some morbidity and mortality.
Review
- Radiologic imaging in rhinosinusitis
Imaging may be necessary for rhinosinusitis that is refractory, chronic, recurrent, or complicated.
Medical Grand Rounds
- A practical program for preventing delirium in hospitalized elderly patients
Delirium in hospitalized elderly patients is common, often unrecognized, and can lead to serious complications. A systematic program can improve the rate of recognition and decrease the rate of incidence.
Review
- Safe use of opioids in chronic noncancer pain
Many physicians needlessly avoid prescribing opioid analgesics for chronic pain because of misconceptions about efficacy, adverse effects, abuse, and addiction potential.
- A guide to informed consent for clinician-investigators
Informed consent is a process, not a form. It is a legal and ethical safeguard to ensure that subjects enter studies voluntarily and fully informed.
Commentary
Are all selective COX-2 inhibitors associated with an increased risk for thromboembolic cardiovascular events? And what should we tell patients?