Table of Contents
November 01, 2005; Volume 72, Issue 11-
From the Editor
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A syringe in the hand is worth two birds in the bush
Brian F. Mandell, MD, PhD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 962;
Short of a true pandemic, there is much we can do to make the 2005–2006 flu season a kinder, gentler one.
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Current Drug Therapy
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DHEA supplementation: The claims in perspective
Ewa Olech, MD and Joan T. Merrill, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 965-984;
Low DHEA levels are seen in a variety of diseases, but whether supplemental DHEA will help remains unproven.
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Safety of statins: Effects on muscle and the liver
Abu R. Vasudevan, MBBS, MD, MRCP, Yasmin S. Hamirani, MBBS and Peter H. Jones, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 990-1001;
Hepatotoxicity and myopathy are uncommon but worrisome. ALT and AST should be measured at baseline and periodically during statin therapy.
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Review
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Hepatitis C infection: A systemic disease with extrahepatic manifestations
Aman Ali, MD and Nizar N. Zein, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1005-1019;
Almost 40% of patients with hepatitis C develop at least one extrahepatic manifestation during the course of the disease.
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The Clinical Picture
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A 73-year-old woman with chronic nonhealing cellulitis
Marc Williams, MD, Anthony K. Leung, DO and Wendy S. Armstrong, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1022-1024;
She has undergone extensive treatment with antibiotics and corticosteroids, without success. What is the likely diagnosis?
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Review
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Anemia in chronic heart failure: Can EPO reduce deaths?
Srinivas Iyengar, MD and William T. Abraham, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1027-1032;
Many patients with chronic heart failure also have anemia, but whether treating the anemia will improve outcomes has yet to be determined.
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Current Drug Therapy
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What is a ‘failure’ of bisphosphonate therapy for osteoporosis?
John J. Carey, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1033-1039;
Assessing the effectiveness of bisphosphonate therapy is problematic. The true measure is prevention of new fractures.
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Medical Grand Rounds
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Influenza 2005–2006
Sherif B. Mossad, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1041-1047;
Behind the preparation for the current influenza season are fears that the simmering outbreak of avian influenza in animals could lead to a pandemic in humans.
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Im Board Review
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A 39-year-old man with sudden onset of chest pain
James K. Stoller, MD, Prashanth R. Sunkureddi, MD, Emilio B. Gonzalez, MD, Rickey Washington, MD, Andres Salazar, MD and Paul Douglass, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1050-1056;
He has a history of a transient ischemic attack and poorly controlled hypertension. What is the likely diagnosis?
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Departments
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Pulmonary embolism imaging (SEPTEMBER 2005)
Michael Emmett, MD and Joseph M. Rothstein, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1059;
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In reply: Pulmonary embolism imaging (SEPTEMBER 2005)
Ruffin J. Graham, MD and Joseph W. Stengel, MD- Cleveland Clinic Journal of Medicine November 2005, 72 (11) 1059;
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