Table of Contents
From the Editor
- Kidneys have a lot of nerve
Renal denervation shows promise. But hypertension is a heterogeneous condition, and the patient’s underlying pathophysiology may dictate the response to this physiologically based therapy.
Review
- POLST: An improvement over traditional advance directives
Physician Orders for Life-Sustaining Treatment (POLST) is a process that translates a patient’s goals for care at the end of life into medical orders.
- Dengue: A reemerging concern for travelers
Dengue, a neglected tropical disease that is reemerging around the world, became a nationally notifiable disease in the United States in 2009.
- Aortic stenosis: Who should undergo surgery, transcatheter valve replacement?
For some patients with aortic stenosis, the choice of management is simple; for others it is less so.
Renal denervation to treat resistant hypertension: Guarded optimismCan a percutaneous catheter-based procedure cure resistant hypertension? The limited data available so far look good.
The Clinical Picture
- A farmer with chest pain and lung nodules
The patient, age 50, was treated 25 years ago for brucellosis. But he is also a 30-pack-year smoker. What does he have?
- Patchy hair loss on the scalp
A 12-year-old girl has a large, irregular area of hair loss. What is going on?
Editorial
- Challenges in the management of aortic stenosis
Unfortunately, physicians who manage aortic stenosis do not encounter straightforward classic cases very often.
- The promise of renal denervation
Only with further carefully conducted randomized trials of renal denervation will its full promise be realized.
