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Cleveland Clinic Journal of Medicine

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Article

Alternative interventions for obstructive sleep apnea

Tina Waters, MD
Cleveland Clinic Journal of Medicine September 2019, 86 (9 suppl 1) 34-41; DOI: https://doi.org/10.3949/ccjm.86.s1.06
Tina Waters
Sleep Disorders Center, Neurological Institute, Cleveland Clinic
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  • For correspondence: [email protected]
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    Figure 1

    Hypoglossal nerve stimulation consists of an implanted pulse generator, sensing lead, and stimulation lead.

    Used with permission from Inspire Medical Systems, Inc.

Tables

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    TABLE 1

    OSA surgical procedures and reported outcomes

    ProcedureOutcome
    Nasal surgery aloneLimited efficacy; 15.8% success rate in patients with OSA with snoring and nasal congestion
    Tracheostomy100% success rate; 83% cure; morbid procedure; last resort
    Laser-assisted uvulopalatoplasty18% reduction in AHI
    Radiofrequency ablation34% reduction in AHI
    Implants25% reduction in AHI
    Uvulopalatopharyngoplasty33% reduction in AHI
    Maxillomandibular advancement87% reduction in AHI
    Bariatric surgery75% improvement in AHI
    • Data from references 8 and 16.

    • AHI = apnea-hypopnea index; OSA = obstructive sleep apnea

    • View popup
    TABLE 2

    Hypoglossal nerve stimulation indications and contraindications

    IndicationsContraindications
    • Age greater than 22
    • Apnea-hypopnea index of 15-65 events per hour (< 25% central or mixed apneic events on polysomnography)
    • Body mass index < 32 kg/m2
    • Failure of or intolerant to positive airway pressure therapy
    • Airway anatomy appropriate on drug-induced sleep endoscopy (no concentric collapse at retropalatal level)
    • > 25% central or mixed apneic events on polysomnography
    • Anatomic findings that compromise performance (ie, complete concentric collapse)
    • Pre-existing condition that compromises neurologic control of the upper airway
    • Inability to operate the system
    • Pregnancy or planning to become pregnant
    • Require magnetic resonance imaging (in some cases)
    • View popup
    TABLE 3

    Oral appliance therapy indications and contraindications

    IndicationsContraindications
    • Younger age• Recent or active orthodontics
    • Lower body mass index• Periodontally compromised dentition
    • Smaller neck size• Acute temporomandibular joint dysfunction
    • Lower apnea-hypopnea index• Unrealistic expectations
    • Positional obstructive sleep apnea• Uncontrolled seizure disorder
    • Retrognathia• Growth potential (orthodontist supervision)
    • Good ability to advance mandible• Limited ability to advance mandible
    • View popup
    TABLE 4

    Patient characteristics that influence the type of oral appliance used

    Number of teeth
    Bruxism
    Nasal or oral breather
    Occlusal scheme
    Overbite and overjet
    Angulation of teeth
    Periodontal health status
    Size of mouth
    Gag reflex
    Mental and physical capabilities and dexterity
    Material allergy
    Sleep position
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Cleveland Clinic Journal of Medicine: 86 (9 suppl 1)
Cleveland Clinic Journal of Medicine
Vol. 86, Issue 9 suppl 1
1 Sep 2019
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Alternative interventions for obstructive sleep apnea
Tina Waters
Cleveland Clinic Journal of Medicine Sep 2019, 86 (9 suppl 1) 34-41; DOI: 10.3949/ccjm.86.s1.06

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Alternative interventions for obstructive sleep apnea
Tina Waters
Cleveland Clinic Journal of Medicine Sep 2019, 86 (9 suppl 1) 34-41; DOI: 10.3949/ccjm.86.s1.06
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  • Article
    • ABSTRACT
    • LIFESTYLE INTERVENTIONS
    • SURGICAL INTERVENTIONS
    • HYPOGLOSSAL NERVE STIMULATION
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