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1-Minute Consult

When is contrast needed for abdominal and pelvic CT?

Mark Radetic, MD, Robert DeVita, MD and John Haaga, MD
Cleveland Clinic Journal of Medicine October 2020, 87 (10) 595-598; DOI: https://doi.org/10.3949/ccjm.87a.19093
Mark Radetic
Department of Internal Medicine, Cleveland Clinic
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  • For correspondence: [email protected]
Robert DeVita
Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH
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John Haaga
Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH
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    Figure 1

    Computed tomography with intravenous contrast enhancement in a patient with right-lower-quadrant abdominal pain. Axial (A) and coronal (B) views reveal diffuse mural and periappendiceal edema, with thickening of the appendix (red arrows). Coarse calcification within the appendix (yellow arrow) likely represents an appendicolith.

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    Figure 2

    Computed tomography with a neutral oral contrast agent. Axial (A) and coronal (B) views reveal multiple loops of dilated bowel (red arrows) with a transition point—ie, site of sudden luminal narrowing (yellow arrows)—in the left lower quadrant, findings consistent with a small-bowel obstruction.

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    TABLE 1

    Indications for intravenous contrast in abdominal and pelvic computed tomography

    Intravenous contrast required
    Gastrointestinal conditions
     Acute abdominal pain
     Abdominal trauma
     Abdominal mass
     Abdominal infection
     Gastrointestinal bleeding (if endoscopy is negative, use computed tomography angiography)
     Pancreatitis
     Liver cancer
     Cirrhosis
     Portal vein thrombosis
     Biliary obstruction
     Inflammatory bowel disease
     Small-bowel obstruction
     Appendicitis
     Diverticulitis
     Colitis
    Urinary tract conditions
     Renal trauma
     Pyelonephritis
     Adrenal mass, cancer
     Renal mass, cancer
     Bladder mass, cancer
    Vascular conditions (CT angiography required)
     Aortic dissection
     Abdominal aortic aneurysm
     Renovascular hypertension
    Intravenous contrast not required
    Hematoma
    Bowel perforation/free air
    Nephrolithiasis
    Colon cancer screening (CT colonography)
    • Based on information in reference 3.

    • View popup
    TABLE 2

    Premedication regimens for patients allergic to intravenous contrast

    Elective (12- or 13-hour) regimen
    Oral regimens
     Prednisone 50 mg at 13 hours, 7 hours, and 1 hour before contrast administration, with or without diphenhydraminea 50 mg 1 hour before contrast administration
     Methylprednisolone 32 mg at 12 and 2 hours before contrast administration, with or without diphenhydraminea 50 mg 1 hour before contrast
    Intravenous regimen (for patients unable to take medications by mouth)
     Hydrocortisone 200 mg at 13 hours, 7 hours, and 1 hour before contrast administration, with or without diphenhydraminea 50 mg 1 hour before contrast administration
    Emergency regimen
    Methylprednisolone 40 mg or hydrocortisone 200 mg immediately, then every 4 hours until contrast administration, with or without diphenhydraminea 50 mg 1 hour before contrast administration
    • ↵a The addition of diphenhydramine is optional. Evidence on its value is mixed.

    • Based on information in reference 8.

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Cleveland Clinic Journal of Medicine: 87 (10)
Cleveland Clinic Journal of Medicine
Vol. 87, Issue 10
1 Oct 2020
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When is contrast needed for abdominal and pelvic CT?
Mark Radetic, Robert DeVita, John Haaga
Cleveland Clinic Journal of Medicine Oct 2020, 87 (10) 595-598; DOI: 10.3949/ccjm.87a.19093

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When is contrast needed for abdominal and pelvic CT?
Mark Radetic, Robert DeVita, John Haaga
Cleveland Clinic Journal of Medicine Oct 2020, 87 (10) 595-598; DOI: 10.3949/ccjm.87a.19093
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    • INTRAVENOUS CONTRAST
    • ORAL CONTRAST
    • GENERAL INDICATIONS FOR CONTRAST USE IN ABDOMINOPELVIC CT
    • ADVERSE EFFECTS OF CONTRAST
    • REFERENCES
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