Hepatology
- What screening approach could improve early detection of ‘at-risk’ metabolic dysfunction–associated steatohepatitis in my patients?
Screening for MASH follows a stepwise, sequential approach, beginning with calculation of the fibrosis-4 index
- ‘Even when the wound is healed, the scar remains’
Persistent or repetitive inflammatory or ischemic insults to internal organs may lead to progressive scarring that culminates in organ failure.
- Unexplained liver injury: Searching for the cause
The patient presented with persistent low back pain, nausea, poor appetite, and an unintentional weight loss of more than 30 lb over the previous 6 weeks.
- Reversing fibrosis in metabolic dysfunction–associated steatohepatitis—beyond telling patients to lose weight
Weight loss of at least 10% is associated with fibrosis regression in most patients, but losing this amount of weight and keeping it off is challenging, making pharmacologic and procedural interventions essential tools in clinical practice.
- Preventing cirrhosis: Why primary care clinicians should screen for liver disease in patients who drink heavily
Clinicians in the primary care setting can identify patients with heavy alcohol use and alcohol-related liver disease before they develop advanced liver damage.
- Does my patient with acute variceal hemorrhage need a transjugular intrahepatic portosystemic shunt?
Placement of a transjugular intrahepatic portosystemic shunt can be used as salvage therapy to control bleeding when endoscopic management fails and as a means of secondary prophylaxis in select patients.
- What are the management considerations for venous thromboembolic events in patients with cirrhosis?
The authors review the current evidence on venous thromboembolic event (VTE) risk prediction in patients with cirrhosis, as well as VTE prophylaxis and anticoagulant therapy.
- Anchors away
Before you read this, I recommend that you read the interesting article in this issue by Prakash et al, part of our Symptoms to Diagnosis series.