Hepatology

  • Pediatric cholestatic liver disease: Successful transition of care
    Pediatric cholestatic liver disease: Successful transition of care
    Praveen Kumar Conjeevaram Selvakumar, MD, Vera Hupertz, MD, Naveen Mittal, MD, Kris V. Kowdley, MD and Naim Alkhouri, MD
    Cleveland Clinic Journal of Medicine July 2019, 86 (7) 454-464; DOI: https://doi.org/10.3949/ccjm.86a.18140

    Many more children with liver disease are surviving into adulthood and transitioning to adult care.

  • A woman, age 35, with new-onset ascites
    William C. Lippert, MD, MPH, Eun Y. Lee, MD and Aibek E. Mirrakhimov, MD
    Cleveland Clinic Journal of Medicine April 2019, 86 (4) 257-262; DOI: https://doi.org/10.3949/ccjm.86a.17082

    She also has jaundice, hepatomegaly, and multiple abnormal laboratory results. What is the next step?

  • The tests that we order define us
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine March 2019, 86 (3) 150; DOI: https://doi.org/10.3949/ccjm.86b.03019

    In practice we balance the inputs from Watson, “Dr. Google,” our experience, and the specific data from the patient.

  • Assessing liver fibrosis without biopsy in patients with HCV or NAFLD
    Tavankit Singh, MD, Daniela S. Allende, MD and Arthur J. McCullough, MD
    Cleveland Clinic Journal of Medicine March 2019, 86 (3) 179-186; DOI: https://doi.org/10.3949/ccjm.86a.17118

    Biopsy is still the gold standard, but methods based on clinical information and on imaging are emerging.

  • Beta-cell therapies for type 1 diabetes: Transplants and bionics
    Beta-cell therapies for type 1 diabetes: Transplants and bionics
    Kathryn Bux Rodeman, MD and Betul Hatipoglu, MD
    Cleveland Clinic Journal of Medicine December 2018, 85 (12) 931-937; DOI: https://doi.org/10.3949/ccjm.85a.17088

    Chief among the challenges: millions of people have diabetes.

  • Liver enzymes, August 2018
    Cleveland Clinic Journal of Medicine October 2018, 85 (10) 737;

    Agganis B, Lee D, Sepe T. Liver enzymes: No trivial elevations, even if asymptomatic. Cleve Clin J Med 2018; 85(8):612–617. doi:10.3949/ccjm.85a.17103

  • The bias of word choice and the interpretation of laboratory tests
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2018, 85 (8) 577-578; DOI: https://doi.org/10.3949/ccjm.85b.08018

    Words matter. Calling ALT and AST “liver function tests” can lead to premature diagnosis of liver disease.

  • Palmoplantar exanthema and liver dysfunction
    Tatsuya Fujikawa, MD, PhD and Hiroki Matsuura, MD
    Cleveland Clinic Journal of Medicine August 2018, 85 (8) 591-593; DOI: https://doi.org/10.3949/ccjm.85a.17060

    The patient admitted to having had unprotected sex with a female sex worker.

  • Liver enzymes: No trivial elevations, even if asymptomatic
    Brian Agganis, MD, David Lee, MD and Thomas Sepe, MD
    Cleveland Clinic Journal of Medicine August 2018, 85 (8) 612-617; DOI: https://doi.org/10.3949/ccjm.85a.17103

    All persistent elevations of liver enzymes need a methodical evaluation and an appropriate working diagnosis.

  • What is the hepatitis B vaccination regimen in chronic kidney disease?
    Kheng Yong Ong, BSc (Pharm) (Hons), Hong Yun Wong, BSc (Pharm) (Hons) and Giat Yeng Khee, PharmD
    Cleveland Clinic Journal of Medicine January 2018, 85 (1) 32-34; DOI: https://doi.org/10.3949/ccjm.85a.17017

    For those with advanced chronic kidney disease, the authors recommend a higher dose, more doses, or both.

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