Should we give triple therapy to patients with atrial fibrillation after percutaneous intervention?

Article Figures & Data

TABLE 1

Anticoagulation after percutaneous coronary intervention in patients with atrial fibrillation

Time after PCI	Low risk of stroke, low risk of bleeding^{^a}	High risk of stroke, low risk of bleeding	Low risk of stroke, high risk of bleeding
0–1 month	DOAC plus P2Y₁₂ inhibitor	DOAC plus P2Y₁₂ inhibitor plus aspirin	DOAC plus P2Y₁₂ inhibitor
1–6 months	DOAC plus P2Y₁₂ inhibitor	DOAC plus P2Y₁₂ inhibitor	DOAC plus P2Y₁₂ inhibitor
6–12 months	DOAC plus P2Y₁₂ inhibitor	DOAC plus P2Y₁₂ inhibitor	DOAC only
After 12 months	DOAC only, discuss risks and benefits	DOAC only, discuss risks and benefits	DOAC only, discuss risks and benefits

↵a For example, with CHA₂DS₂-VASc score of 0 or 1 and HAS-BLED score of 0–2.
DOAC = direct-acting oral anticoagulant; PCI = percutaneous coronary intervention