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The Clinical Picture

A brownish erythematous patch in the nipple-areola complex

Irene López Riquelme, MD, Elisabeth Gómez Moyano, MD, PhD, María Ayala Blanca, PhD and Leandro Martínez Pilar, MD, PhD
Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: https://doi.org/10.3949/ccjm.89a.21059
Irene López Riquelme
Department of Dermatology, Hospital Regional Universitario de Málaga, Málaga, Spain
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  • For correspondence: [email protected]
Elisabeth Gómez Moyano
Department of Dermatology, Hospital Regional Universitario de Málaga, Málaga, Spain
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María Ayala Blanca
Department of Pathology, Hospital Regional Universitario de Málaga, Málaga, Spain
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Leandro Martínez Pilar
Department of Dermatology, Hospital Regional Universitario de Málaga, Málaga, Spain
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    Figure 1

    Brownish erythematous patch in the nipple-areola complex.

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    Figure 2

    Skin biopsy showing single cells and small clusters of neoplastic cells (arrows) through the epidermis, with abundant pale cytoplasm (hematoxylin and eosin, × 400).

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    Figure 3

    Strong staining of the surgical specimen with cytokeratin 7 in the surgical specimen confirmed the presence of cohesive neoplastic cells in the ductal lumen.

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Cleveland Clinic Journal of Medicine: 89 (5)
Cleveland Clinic Journal of Medicine
Vol. 89, Issue 5
1 May 2022
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A brownish erythematous patch in the nipple-areola complex
Irene López Riquelme, Elisabeth Gómez Moyano, María Ayala Blanca, Leandro Martínez Pilar
Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: 10.3949/ccjm.89a.21059

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A brownish erythematous patch in the nipple-areola complex
Irene López Riquelme, Elisabeth Gómez Moyano, María Ayala Blanca, Leandro Martínez Pilar
Cleveland Clinic Journal of Medicine May 2022, 89 (5) 241-242; DOI: 10.3949/ccjm.89a.21059
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