Table of Contents

What mechanisms might account for the diverse beneficial effects of the SGLT-2 inhibitors observed across various diseases?

A 60-year-old man presented with a 20-year history of slowly worsening prominent veins in both lower limbs.

Patients with sepsis who do not need vasopressors do not benefit from intravenous albumin compared with intravenous crystalloid therapy alone.

Placement of a transjugular intrahepatic portosystemic shunt can be used as salvage therapy to control bleeding when endoscopic management fails and as a means of secondary prophylaxis in select patients.

This review summarizes recent data and guidelines regarding SGLT-2 inhibitors in heart failure and chronic kidney disease and provides practical guidance for their use.

Lymphedema, lipedema, and even simple obesity in the extremities can resemble each other superficially and are often confused for one another, but they differ in important ways.

The authors review clinical aspects of herpes zoster vaccination, including identifying at-risk patients, weighing the risks and benefits of the recombinant zoster vaccine, and using best practices for administering the vaccine.