Table of Contents

Patients with uric acid renal calculi are best treated with hydration and urinary alkalinization, not surgery or lithotripsy.

The usual cause of hypersensitivity vasculitis is exposure to a drug or toxin, but infection, Henoch Schönlein purpura, and connective tissue diseases also are possible.

An innovative series will address issues in basic science that are relevant to the practice of medicine.

A program involving rabbit and human protocols demonstrates the successful integration of basic and clinical research with practical applications.

Generalized pruritus that does not respond quickly to symptomatic therapy requires careful evaluation and close follow-up.

Dr. Stanley Hoerr left his colleagues and friends with a legacy of compassion, leadership, and integrity.

An easy-to-learn alternative to the Unna boot is effective and well accepted by patients, with minimal risk of complications.

Parkinson’s patients treated with deprenyl note modest but consistent clinical improvement.

The effects of rt-PA on platelet activity could have a direct impact on thrombolytic efficacy, coronary artery reocclusion, and risk of hemorrhage.

For routine purposes, measurement of slowly catabolized enzymes is the most practical way to determine infarct size.

The electrocardiogram gives a reasonable estimate of infarct size; among visual methods, magnetic resonance imaging has the greatest potential for accuracy.

Despite therapeutic advances, infective endocarditis still has an overall mortality of 20%; transesophageal echocardiography may improve the management of these patients.

Future alternatives to traditional insulin administration include closed-loop delivery systems and islet cell transplantation.

With improved immunosuppressive therapy, pancreas transplantation may become an option for diabetic patients early in the course of their disease.

A monocytic leukemoid reaction in a patient with myelodysplastic syndrome was related to the effect of corticosteroids on the underlying marrow disorder.

Darier’s type of transient acantholytic dermatosis developed in a patient with myelodysplasia and was treated with steroids and antihistamines.