Table of Contents
From the Editor
- The return of The Clinical Picture
Sharpen your powers of observation with our revived question-and-answer quiz.
1-Minute Consult
- Should patients receiving long-term gastric acid inhibition therapy be evaluated for vitamin B12 deficiency?
Very few patients actually deplete their body stores of vitamin B12 but supplementation is benign.
Im Board Review
- A 65-year-old factory worke with dyspnea on exertion and a normal chest x-ray
What is the cause of this patient’s symptoms? A self-test on a clinical case.
Medical Grand Rounds
- Heart failure is a fever: The cytokine connection
The discovery that inflammation contributes to heart failure may lead to new therapies for this disease.
- In diabetes, treat hidden heart disease
Both diabetic and prediabetic patients have abnormal vascular reactivity and should be considered to have occult cardiovascular disease.
The Clinical Picture
Patient Information
Review
- Pharmacologic aids to smoking cessation
Quitting smoking is notoriously hard. Drugs can improve the odds of quitting, but the best approach is multifactorial.
- Factor V Leiden and Prothrombin G20210A
Genetic testing is useful only if the knowledge gained will affect the course of treatment.
Cancer Diagnosis and Management
- Treatment of ovarian cancers not of epithelial origin
Some ovarian cancers carry a prognosis quite different from that of epithelial ovarian cancer, and call for totally different treatment.
Review
- Using troponin T to diagnose acute coronary syndromes
Troponin T and creatine kinase MB have complementary roles. Includes a diagnostic algorithm.
- Carotid stenosis: Current strategies for choosing between medical and surgical management
Recommendations on a longstanding and contentious issue.