Table of Contents

October 01, 2006; Volume 73,Issue 10

From the Editor

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Oil it where it squeaks: Evidence, experience, and osteoarthritis therapy
Brian F. Mandell, MD, PhD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 880;

Since many patients with osteoarthritis do experience relief with intra-articular therapy, it may indeed pay to “oil it where it squeaks.” I just wonder how much it matters what oil we use.

1-Minute Consult

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Are statins ‘smart bombs’? (August 2006)
Luca Mascitelli, MD and Francesca Pezzetta, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 881;

Review

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In reply: Are statins ‘smart bombs’? (August 2006)
Mehdi H. Shishehbor, DO, MPH and Deepak L. Bhatt, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 881-884;
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When can patients with acute deep vein thrombosis be allowed to get up and walk?
Leonard S. Feldman, MD and Daniel J. Brotman, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 893-896;

They should ambulate as tolerated. Bed rest is not evidence-based and may be harmful.
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Intra-articular injections for osteoarthritis of the knee
David H. Neustadt, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 897-911;

If usual medical measures fail to control the pain of osteoarthritis of the knee, intra-articular injections of a corticosteroid, a hyaluronan, or both may help.

Current Drug Therapy

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Recurrent pregnancy loss: Evaluation and discussion of the causes and their management
Robert Kiwi, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 913-921;

Women who miscarry two or more consecutive pregnancies deserve an evaluation to look for the cause, which sometimes can be treated.

Interpreting Key Trials

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Headaches in older patients: Special problems and concerns
Robert S. Kunkel, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 922-928;

Any patient older than 50 years who develops headaches for the first time or who has a change in a chronic headache pattern should be investigated for an underlying cause or exacerbating condition.

Review

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Using the new HPV vaccines in clinical practice
Lea E. Widdice, MD and Jessica A. Kahn, MD, MPH

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 929-935;

The new vaccines against human papillomavirus (HPV) could prevent up to 70% of cases of cervical cancer. But Pap testing will still be necessary.

Departments

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Interpreting the ASTEROID Trial
Ilke Sipahi, MD, Stephen J. Nicholls, MBBS, PhD, E. Murat Tuzcu, MD and Steven E. Nissen, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 937-944;

The optimal strategy for lipid-lowering in patients with coronary artery disease may be to aim for the lowest low-density lipoprotein cholesterol level that can be attained without adverse effects.
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Beyond cardiovascular risk: The impact of obesity on cancer death
Bryan C. Bordeaux, DO, MPH, Shari Bolen, MD, MPH and Daniel J. Brotman, MD

Cleveland Clinic Journal of Medicine October 2006, 73 (10) 945-950;

We summarize the evidence supporting a link between obesity and cancer, discuss possible explanations, and recommend ways to enhance cancer prevention.