Table of Contents
From the Editor
- Oil it where it squeaks: Evidence, experience, and osteoarthritis therapy
Since many patients with osteoarthritis do experience relief with intra-articular therapy, it may indeed pay to “oil it where it squeaks.” I just wonder how much it matters what oil we use.
1-Minute Consult
Review
- When can patients with acute deep vein thrombosis be allowed to get up and walk?
They should ambulate as tolerated. Bed rest is not evidence-based and may be harmful.
- Intra-articular injections for osteoarthritis of the knee
If usual medical measures fail to control the pain of osteoarthritis of the knee, intra-articular injections of a corticosteroid, a hyaluronan, or both may help.
Current Drug Therapy
- Recurrent pregnancy loss: Evaluation and discussion of the causes and their management
Women who miscarry two or more consecutive pregnancies deserve an evaluation to look for the cause, which sometimes can be treated.
Interpreting Key Trials
- Headaches in older patients: Special problems and concerns
Any patient older than 50 years who develops headaches for the first time or who has a change in a chronic headache pattern should be investigated for an underlying cause or exacerbating condition.
Review
- Using the new HPV vaccines in clinical practice
The new vaccines against human papillomavirus (HPV) could prevent up to 70% of cases of cervical cancer. But Pap testing will still be necessary.
Departments
- Interpreting the ASTEROID Trial
The optimal strategy for lipid-lowering in patients with coronary artery disease may be to aim for the lowest low-density lipoprotein cholesterol level that can be attained without adverse effects.
- Beyond cardiovascular risk: The impact of obesity on cancer death
We summarize the evidence supporting a link between obesity and cancer, discuss possible explanations, and recommend ways to enhance cancer prevention.