Table of Contents

Different generations of physicians have proposed various contenders for the title of “great masquerader.” I firmly believe that Clostridium difficile infection deserves a shot at the title.

She has headache, new-onset seizures, edema, and proteinuria; her blood pressure is 235/114 mm Hg and she weighs 256 lb. What is the diagnosis?

PTSD not only affects soldiers, it also occurs in civilians exposed to severe trauma or serious illness. Manifestations commonly include nonspecific physical symptoms, and patients often present to their primary care physician.

Patients with frequent and recurrent respiratory infections should be tested for immune system abnormalities. This article describes common primary and secondary forms of hypogammaglobulinemia and how to evaluate and manage them.

BNP assays are now widely used to evaluate suspected heart failure, but they should not be the only criterion.

Nephrotic syndrome now has a dramatically different prognosis than it did 10 years ago. We can now effectively treat all types and achieve remission in many cases.

The lesion, originally diagnosed as pyoderma gangrenosum, now measures 15 cm × 6 cm. What should be the next step in management?

Disease-modifying therapies have been a big advance in multiple sclerosis, but many patients still experience a variety of symptoms that reduce quality of life. We have to treat the whole patient.

Clostridium difficile-associated disease (CDAD) is increasing in incidence and severity and may be becoming more difficult to treat. A new strain is causing many outbreaks.