Table of Contents

January 01, 2010; Volume 77,Issue 1

From the Editor

You have access
Evidence, limes, and cement
Brian F. Mandell, MD, PhD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 7; DOI: https://doi.org/10.3949/ccjm/77a.01001

Sometimes, the results of clinical trials do not immediately affect what physicians do because the results do not jibe with experience.

Commentaries

You have access
Vertebroplasty, cognitive dissonance, and evidence-based medicine: What do we do when the ‘evidence’ says we are wrong?
R. Douglas Orr, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 8-11; DOI: https://doi.org/10.3949/ccjm.77a.09146

Two recent trials call into question the efficacy of vertebroplasty for treating osteoporotic vertebral compression fractures and are leading many of us to question our assumptions about vertebroplasty.
You have access
Consternation and questions about two vertebroplasty trials
Marcy B. Bolster, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 12-16; DOI: https://doi.org/10.3949/ccjm.77a.09161

Should we abandon this popular procedure? Or are there considerations that may mitigate the negative findings of these two trials?

Current Drug Therapy

You have access
Acetaminophen: Old drug, new warnings
Amy Schilling, PharmD, Rebecca Corey, PharmD, BCPS, Mandy Leonard, PharmD, BCPS and Bijan Eghtesad, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 19-27; DOI: https://doi.org/10.3949/ccjm.77a.09084

Often, patients overdose because they take more than one acetaminophen product and are unaware that both products contain the drug.

The Clinical Picture

You have access
Lesions on the hands, high aminotransferase levels
Manuel Gil-Mosquera, MD, Sergio Vañó-Galván, MD, Ruth Gomez-Guerra, MD, Pedro Jaén, MD and Marina Gil-Mosquera, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 34-36; DOI: https://doi.org/10.3949/ccjm.77a.08104

A 64-year-old man presents with a 10-day history of painful vesicles and erosions on the dorsa of the hands that appeared after sun exposure. What is the diagnosis?

Review

You have access
Myelodysplastic syndromes: A practical approach to diagnosis and treatment
Afsaneh Barzi, MD and Mikkael A. Sekeres, MD, MS

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 37-44; DOI: https://doi.org/10.3949/ccjm.77a.09069

The myelodysplastic syndromes are clonal bone marrow disorders that lead to underproduction of normal blood cells. Primary care physicians tend to be the first to identify the problem.
You have access
Food allergy and eosinophilic esophagitis: Learning what to avoid
Sandra Hong, MD and Nicola M. Vogel, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 51-59; DOI: https://doi.org/10.3949/ccjm.77a.09018

What we know about the mechanisms of food allergies and eosinophilic esophagitis, how to diagnose them, and how to treat them.

Im Board Review

You have access
Abdominal pain in a 20-year-old woman
Lakshmi S. Pasumarthy, MD, Duane E. Ahlbrandt, MD and James W. Srour, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 45-50; DOI: https://doi.org/10.3949/ccjm.77a.09067

Her body mass index is 18.7, and she has lost 20 lb despite a good appetite. What is the cause?

1-Minute Consult

You have access
Should we routinely screen for hypercapnia in sleep apnea patients before elective noncardiac surgery?
Babak Mokhlesi, MD, MSc, Leif Saager, MD and Roop Kaw, MD

Cleveland Clinic Journal of Medicine January 2010, 77 (1) 60-61; DOI: https://doi.org/10.3949/ccjm.77a.09105

Yes. Obesity hypoventilation syndrome is often undiagnosed and greatly increases perioperative risk.