Table of Contents
From the Editor
- The bias of word choice and the interpretation of laboratory tests
Words matter. Calling ALT and AST “liver function tests” can lead to premature diagnosis of liver disease.
The Clinical Picture
- Angular cheilitis induced by iron deficiency anemia
Causes include nutritional deficiencies, local and systemic factors, and drug treatment.
- Calcific uremic arteriolopathy
A 51-year-old man with end-stage renal disease presented with extensive necrotic ulcers and eschar on both legs.
- Palmoplantar exanthema and liver dysfunction
The patient admitted to having had unprotected sex with a female sex worker.
Medical Grand Rounds
- Diagnosing and treating bipolar disorder in primary care
Many patients have undiagnosed bipolar depression, ie, depression with shifts to periods of mania.
1-Minute Consult
- Which patients with a parapneumonic effusion need a chest tube?
Hospitalized patients with pneumonia who develop a complicated effusion or empyema need one.
Review
- Liver enzymes: No trivial elevations, even if asymptomatic
All persistent elevations of liver enzymes need a methodical evaluation and an appropriate working diagnosis.
- Diabetes and pregnancy: Risks and opportunities
Internists can reduce the risks by optimizing glycemic control before conception and providing effective counseling.
- Phosphorus binders: The new and the old, and how to choose
The pathophysiology and control of hyperphosphatemia in kidney disease, focusing on phosphorus binders.
Editorial
- Phosphorus in kidney disease: Culprit or bystander?
As kidney function declines, phosphorus accumulates, but the process is complex.