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Review

Human papillomavirus in 2019: An update on cervical cancer prevention and screening guidelines

Salina Zhang, BS and Pelin Batur, MD, NCMP, CCD
Cleveland Clinic Journal of Medicine March 2019, 86 (3) 173-178; DOI: https://doi.org/10.3949/ccjm.86a.18018
Salina Zhang
Case Western Reserve University School of Medicine, Cleveland, OH
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Pelin Batur
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  • For correspondence: [email protected]
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    TABLE 1

    HPV vaccination timeline, male and female

    Age 9–14Age 15–26Age 21–26 (male)Age 27–45
    2-dose HPV vaccine, 0 and 6–12 months3-dose HPV vaccine, 0, 1–2, and 6 monthsVaccine offered, 3-dose regimenFDA-approved, but not routinely recommended
    • FDA = US Food and Drug Administration; HPV = human papillomavirus

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    TABLE 2

    Facts about the human papillomavirus (HPV) vaccine

    The HPV vaccine is safe
    The HPV vaccine causes no bad side effects
    The HPV vaccine does not cause fertility problems
    The HPV vaccine does not contain harmful ingredients
    Getting the HPV vaccine is not opening the door to having sex
    The HPV vaccine is for both males and females
    The HPV vaccine works and can help prevent cervical cancer
    The HPV vaccines last a long time, maybe forever
    • Information from the American Cancer Society, reference 15.

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    TABLE 3

    Cervical cancer screening recommendations, ACOG, ASCCP, USPSTF

    ACOG17ASCCP18USPSTF19
    Pap onlyEvery 3 yearsEvery 3 yearsEvery 3 years
    Pap-HPV cotestEvery 5 years, age 30–65Every 5 years, age 30–65Every 5 years, age 30–65
    High-risk HPV onlyEvery 3 years, age > 25Every 3 years, age > 25Every 5 years, age 30–65
    • ACOG = American College of Obstetricians and Gynecologists; ASCCP = American Society for Colposcopy and Cervical Pathology; HPV = human papillomavirus; USPSTF = US Preventive Services Task Force

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Cleveland Clinic Journal of Medicine: 86 (3)
Cleveland Clinic Journal of Medicine
Vol. 86, Issue 3
1 Mar 2019
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Human papillomavirus in 2019: An update on cervical cancer prevention and screening guidelines
Salina Zhang, Pelin Batur
Cleveland Clinic Journal of Medicine Mar 2019, 86 (3) 173-178; DOI: 10.3949/ccjm.86a.18018

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Human papillomavirus in 2019: An update on cervical cancer prevention and screening guidelines
Salina Zhang, Pelin Batur
Cleveland Clinic Journal of Medicine Mar 2019, 86 (3) 173-178; DOI: 10.3949/ccjm.86a.18018
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  • Article
    • ABSTRACT
    • TYPES OF HPV VACCINES
    • VACCINE DOSING RECOMMENDATIONS FOR PRIMARY PREVENTION
    • CHALLENGES OF VACCINATION
    • SECONDARY PREVENTION: CERVICAL CANCER SCREENING
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