The Clinical Picture

Eruptive seborrheic keratosis: A perilous clue

Akanksha Kaushik, MD, Soufila KT, MD, Manju Daroach, MD, Divya Aggarwal, MD, Pulkit Rastogi, MD, DM and Muthu Sendhil Kumaran, MD, DNB
Cleveland Clinic Journal of Medicine August 2021, 88 (8) 428-430; DOI: https://doi.org/10.3949/ccjm.88a.20124

Article Figures & Data

Figures

  • Figure 1
    Figure 1

    An erythematous, firm, nontender nodule measuring 3 cm × 3 cm in the right midaxillary line.

  • Figure 2
    Figure 2

    Multiple seborrheic keratoses of various sizes arranged in a “Christmas tree” pattern on the patient’s back.

  • Figure 3
    Figure 3

    A: The epidermis appears relatively unremarkable. The dermis shows a mild to moderate degree of perivascular and periadnexal mononuclear inflammatory infiltrate (black arrows) along with a tumor deposit in the deep dermis (red arrow) (hematoxylin and eosin stain; magnification × 20). B: The tumor is composed of cells arranged in small glands (arrow) inciting a desmoplastic reaction. The tumor cells are moderately pleomorphic and have coarse chromatin and a moderate amount of cytoplasm (hematoxylin and eosin stain; magnification × 200). C: Immunostaining shows tumor cells positive for cytokeratin 7 (arrows) (CK 7 immunostain; magnification × 200).

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