Table of Contents

April 01, 2022; Volume 89,Issue 4

From the Editor

  • Treating anemia: It’s not just the EPO
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 174-175; DOI: https://doi.org/10.3949/ccjm.89b.04022

    Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.

The Clinical Picture

  • Oral hyperpigmentation with weakness and salt-craving
    Joseph Zhou, MD and S. Sethu K. Reddy, MD, MBA, FRCPC, FACP, MACE
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 180-181; DOI: https://doi.org/10.3949/ccjm.89a.21036

    The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.

Symptoms to Diagnosis

  • The devil is in the details: Approach to refractory hypokalemia
    Carmen Elena Cervantes, MD, Karthik Meiyappan Udayappan, MD and Duvuru Geetha, MBBS, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 182-188; DOI: https://doi.org/10.3949/ccjm.89a.21013

    The authors illustrate a stepwise approach to the evaluation of acid-base disturbances.

Editorial

  • Glycemic targets in the ICU: A look back, and ahead
    Keren Zhou, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 189-190; DOI: https://doi.org/10.3949/ccjm.89a.21127

    Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.

Review

  • Glycemic control in the critically ill: Less is more
    Ghaith Alhatemi, MD, Haider Aldiwani, MD, Rafal Alhatemi, MD, Marwah Hussein, MD, Suzan Mahdai, MD and Berhane Seyoum, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 191-199; DOI: https://doi.org/10.3949/ccjm.89a.20171

    The authors discuss findings from key trials, metrics of glycemic control, and recommendations of professional societies for target blood glucose ranges in critically ill patients.

  • Capsule endoscopy in gastrointestinal disease: Evaluation, diagnosis, and treatment
    Basil Akpunonu, MD, Jeannine Hummell, CNP, Joseph D. Akpunonu and Shahab Ud Din, MD
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 200-211; DOI: https://doi.org/10.3949/ccjm.89a.20061

    The procedure is mainly used to evaluate obscure bleeding in the small bowel, but it is also used in the evaluation and diagnosis of a wide range of gastrointestinal conditions.

  • Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Anemia of chronic kidney disease: Will new agents deliver on their promise?
    Tarek Souaid, MD, Jonathan Taliercio, DO, James F. Simon, MD, MBA, Ali Mehdi, MD, MEd and Georges N. Nakhoul, MD, MEd
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 212-222; DOI: https://doi.org/10.3949/ccjm.89a.21100

    A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.

Corrections

  • Extraosseous calcification in kidney disease
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 223;

    The following article in the February 2022 issue contained an error: Bartolomeo K, Tan XY, Fatica R. Extraosseous calcification in kidney disease. Cleve Clin J Med 2022; 89(2):81–90. doi:10.3949/ccjm.89a.21073

  • Does my hospitalized patient need an NPO-after-midnight order preoperatively?
    Cleveland Clinic Journal of Medicine April 2022, 89 (4) 223;

    The following article in the February 2022 issue contained an error: Chapman T, Sinz E, McGillen B. Does my hospitalized patient need an NPO-after-midnight order preoperatively? Cleve Clin J Med 2022; 89(2):69–70. doi:10.3949/ccjm.89a.21061

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