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Review

Chronic anal pain: A review of causes, diagnosis, and treatment

Charles H. Knowles, PhD, FRCS, FACCRS (Hons) and Richard C. Cohen, MD, FRCS
Cleveland Clinic Journal of Medicine June 2022, 89 (6) 336-343; DOI: https://doi.org/10.3949/ccjm.89a.21102
Charles H. Knowles
Consultant Colorectal Surgeon, Cleveland Clinic London, UK; Professor of Surgery, Queen Mary University of London, London, UK; Professor of Experimental Therapeutics, University College London; Hon. Consultant Colorectal Surgeon, St Marks Hospital, London, UK; Hon. Professor of Colorectal Surgery, University of Antwerp, Antwerp, Belgium
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  • For correspondence: [email protected]
Richard C. Cohen
Consultant Colorectal Surgeon, Cleveland Clinic London, UK; Professor of Colorectal Surgery, University College London, London, UK
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ABSTRACT

Chronic anal pain is difficult to diagnose and treat, especially with no obvious anorectal cause apparent on clinical examination. This review identifies 3 main diagnostic categories for chronic anal pain: local causes, functional anorectal pain, and neuropathic pain syndromes. Conditions covered within these categories include proctalgia fugax, levator ani syndrome, pudendal neuralgia, and coccygodynia. The signs, symptoms, relevant diagnostic tests, and main treatments for each condition are reviewed.

  • Copyright © 2022 The Cleveland Clinic Foundation. All Rights Reserved.
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  1. Charles H. Knowles, PhD, FRCS, FACCRS (Hons)⇑
  1. Consultant Colorectal Surgeon, Cleveland Clinic London, UK; Professor of Surgery, Queen Mary University of London, London, UK; Professor of Experimental Therapeutics, University College London; Hon. Consultant Colorectal Surgeon, St Marks Hospital, London, UK; Hon. Professor of Colorectal Surgery, University of Antwerp, Antwerp, Belgium
  1. Address:
    Charles H. Knowles, PhD, FRCS, FACCRS (Hons), Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Blizard Institute, 4 Newark St, London E1 2AT; c.h.knowles{at}qmul.ac.uk
  1. Richard C. Cohen, MD, FRCS
  1. Consultant Colorectal Surgeon, Cleveland Clinic London, UK; Professor of Colorectal Surgery, University College London, London, UK

ABSTRACT

Chronic anal pain is difficult to diagnose and treat, especially with no obvious anorectal cause apparent on clinical examination. This review identifies 3 main diagnostic categories for chronic anal pain: local causes, functional anorectal pain, and neuropathic pain syndromes. Conditions covered within these categories include proctalgia fugax, levator ani syndrome, pudendal neuralgia, and coccygodynia. The signs, symptoms, relevant diagnostic tests, and main treatments for each condition are reviewed.

  • Copyright © 2022 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 89 (6)
Cleveland Clinic Journal of Medicine
Vol. 89, Issue 6
1 Jun 2022
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Chronic anal pain: A review of causes, diagnosis, and treatment
Charles H. Knowles, Richard C. Cohen
Cleveland Clinic Journal of Medicine Jun 2022, 89 (6) 336-343; DOI: 10.3949/ccjm.89a.21102

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Chronic anal pain: A review of causes, diagnosis, and treatment
Charles H. Knowles, Richard C. Cohen
Cleveland Clinic Journal of Medicine Jun 2022, 89 (6) 336-343; DOI: 10.3949/ccjm.89a.21102
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  • Article
    • ABSTRACT
    • DIAGNOSTIC APPROACH AND COMMON PITFALLS
    • FUNCTIONAL ANORECTAL PAIN SYNDROMES
    • NEUROPATHIC PAIN SYNDROMES
    • TAKE-HOME MESSAGES
    • DISCLOSURES
    • REFERENCES
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