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Symptoms to Diagnosis

An unexpected turn: A 71-year-old man with myocardial infarction

Smitha Ganeshan, MD, MBA, Benjamin Kelemen, MD, Gurpreet Dhaliwal, MD and Lucas Zier, MD, MS
Cleveland Clinic Journal of Medicine July 2022, 89 (7) 401-407; DOI: https://doi.org/10.3949/ccjm.89a.21030
Smitha Ganeshan
Department of Medicine, University of California San Francisco, San Francisco, CA
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  • For correspondence: Smitha.ganeshan@ucsf.edu
Benjamin Kelemen
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA
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Gurpreet Dhaliwal
Department of Medicine, University of California San Francisco, San Francisco, CA; Medical Service, San Francisco Veterans Affairs Medical Center, San Francisco, CA
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Lucas Zier
Department of Medicine, Division of Cardiology, University of California San Francisco, San Francisco, CA; Zuckerberg San Francisco General Hospital, San Francisco, CA
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    Figure 1

    The patient’s electrocardiogram in the emergency department showed ST-segment elevation (arrows) in leads II, III, and aVF, and ST-segment depressions (triangles) in V1, V2,, V3,, and aVL.

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    Figure 2

    Coronary angiography revealed a left dominant circulation with the posterior descending artery and posterolateral branches arising from the left circumflex artery. A large filling defect was visualized in the left dominant circumflex artery as well as distal cutoffs in multiple obtuse marginal branches.

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    Figure 3

    On repeat electrocardiography 48 hours after presentation, the ST-segment elevations in leads II, III, and aVF were still present. The ST-segment depressions in aVL and V1-V3 had resolved, and new ST-segment elevations were present in V4 and V5 (arrows).

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    Figure 4

    Transesophageal echocardiography on hospital day 3 showed an 8-mm vegetation on the aortic valve (arrow).

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    TABLE 1

    Types of shock

    MechanismPulmonary capillary wedge pressureCardiac outputSystemic vascular resistanceTreatment
    DistributiveLowNormal or highLowPressors
    Intravenous fluids
    Etiology-specific therapies (eg, antibiotics, epinephrine)
    CardiogenicHighLowHighInotropes
    Mechanical circulatory support
    HypovolemicLowNormal or lowNormal or highIntravenous fluids
    Etiology-specific therapies (eg, blood transfusion)
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Cleveland Clinic Journal of Medicine: 89 (7)
Cleveland Clinic Journal of Medicine
Vol. 89, Issue 7
1 Jul 2022
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An unexpected turn: A 71-year-old man with myocardial infarction
Smitha Ganeshan, Benjamin Kelemen, Gurpreet Dhaliwal, Lucas Zier
Cleveland Clinic Journal of Medicine Jul 2022, 89 (7) 401-407; DOI: 10.3949/ccjm.89a.21030

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An unexpected turn: A 71-year-old man with myocardial infarction
Smitha Ganeshan, Benjamin Kelemen, Gurpreet Dhaliwal, Lucas Zier
Cleveland Clinic Journal of Medicine Jul 2022, 89 (7) 401-407; DOI: 10.3949/ccjm.89a.21030
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  • Article
    • FURTHER STUDIES
    • DIFFERENTIAL DIAGNOSIS
    • CASE CONTINUED: RETURN FOR CATHETERIZATION
    • INTERPRETING THE HEMODYNAMIC MEASUREMENTS
    • CASE CONTINUED: REFRACTORY SHOCK, NEW RESULTS
    • INTERPRETING THE NEW ELECTROCARDIOGRAPHIC RESULTS
    • CASE CONTINUED: A DEFINITIVE DIAGNOSIS
    • SEPTIC CORONARY EMBOLIZATION
    • TAKE-HOME POINTS
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