Table of Contents
From the Editor
- Unexplained pathology is not always autoimmune
Our success in understanding well-defined autoimmune diseases may make us too willing to attribute yet-unexplained conditions to autoimmunity simply because they share symptoms.
The Clinical Picture
- Asymptomatic oral plaques and erosion
A 45-year-old man presented with a 4-week history of plaques and erosion on the left buccal mucosa and lower lip.
1-Minute Consult
- How do I diagnose and treat my patient’s amiodarone-induced thyrotoxicosis?
Differentiating type 1 from type 2 amiodarone-induced thyrotoxicosis requires serologic testing, color Doppler ultrasonography, and radioisotope studies, and influences the choice of treatment.
Commentary
- A new paradigm for adult ADHD: A focused strategy to monitor treatment
In adults with attention deficit hyperactivity disorder, shifting the focus of treatment from reducing symptoms to increasing task completions can allow the physician and patient to quickly determine effectiveness of pharmacotherapy.
Review
- Atypical hyperplasia of the breast: Clinical cases and management strategies
The authors describe common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.
Editorial
- Surgical de-escalation: Are we ready for ‘observation’ of benign high-risk breast lesions found on core needle biopsy?
Surgical de-escalation is part of a larger movement of de-escalation of multidisciplinary breast cancer treatment. The challenge is to balance oncologic outcomes with surgical morbidity and quality of life.
Review
Autoimmunity and postural orthostatic tachycardia syndrome: Implications in diagnosis and managementA review of the presentation and diagnostic evaluation, including atypical features that may suggest an alternative diagnosis requiring a more extensive evaluation.
Commentary
The updated guidelines push for less-aggressive management of uncomplicated diverticulitis in select patients.