Article Figures & Data
Figures
- Figure 1
A short axis view of the femoral vein (FV), the femoral artery (FA) at the site of the saphenous vein inflow (SV). Amorphous echogenicity in the femoral vein, greater than that of the adjacent femoral artery is suggestive of “slow venous flow.” The vein is fully compressible ruling out deep vein thrombosis at the site.
Tables
- TABLE 1
Category 1
D-dimer < 3,000 ng/mL
FEU
Standard prophylaxisCategory 2
D-dimer > 3,000 ng/mL
FEU
High-intensity prophylaxisCategory 3
Confirmed VTEStandard dose Enoxaparin 40 mg SC q24h Enoxaparin 40 mg SC q12h IV Heparin DVT/PE nomogram or Enoxaparin 1 mg/kgSC q12h Renal failure
‡AKI definition: Doubling of creatinine in 48h or anuriaCrCI > 10-30mL/min:
Enoxaparin 30 mg SC q24hCrCI < 30 mL/min or AKI:
Enoxaparin 40 mg SC q24hIV heparin DVT/VTE nomogram CrCI < 10 mL/min or
AKI‡:
UFH 5,000 USCq12hCrCI < 10 mL/min or AKI‡:
UFH 7500 U SC ql2hCRRT:
500 U/h through circuit Circuit clotting:
IV ACS nomogramCRRT:
500 U/h through circuit Circuit clotting:
IV ACS nomogramObesity Standard > 100 kg:
Enoxaparin 40 mg SC q12h
> 120 kg:
Enoxaparin 60 mg SC q12h> 100 kg:
Enoxaparin 60 mg SC q12h
> 120 kg:
Enoxaparin 80 mg SC q12hIV Heparin DVT/PE nomogram or Enoxaparin 1 mg/kgSC q12h - up to 150 mg
Above 150 kg use UFHRenal failure
30mL/min or AKI‡
‡AKI definition: Doubling of creatinine in 48h or anuria≤ 120 kg: 7,500 U q12h
> 120kg: 10,000U q12h≤ 120 kg: 7,500 U q8h
> 120kg: 10,000U q8hIV heparin DVT/PE nomogram CRRT:
500 U/h through circuit Circuit clotting:
IV Heparin ACS‡ nomogramCRRT:
500 U/h through circuit Circuit clotting:
IV Heparin ACS‡ nomogramIV Heparin ACS nomogram: initial dose 60-U/kg bolus, 12 U/kg/h
- Target =aPTT49 – 67 seconds
- Target heparin anti-Xa. 0.2 - 0.5 until/mlACS = acute coronary syndrome; AKI = acute kidney injury; aPTT = activated partial thromboplastin time; CrCl = creatinine clearance; CRRT = continuous renal replacement therapy; DVT = deep vein thrombosis; FEU = fibrinogen equivalent units; IV = intravenous; PE = pulmonary embolism; SC = subcutaneously; UFH = unfractionated heparin
