Table of Contents
From the Editor
- The Clinic and the Journal: Respecting the past and welcoming the future
This year is the 100th anniversary of the founding of Cleveland Clinic.
Editorial
- Prostate cancer: To screen or not to screen? The question is complicated
Prostate cancer screening is controversial due to the complexity of harms and benefits.
Commentary
- COVID-19 diagnostic testing and the psychology of precautions fatigue
Overuse of special precautions can lead to diminished vigilance.
The Clinical Picture
- A patient with breast cancer and a rash on her hands and feet
She had completed her third cycle of chemotherapy 3 days earlier.
- Cryptosporidiosis in an immunosuppressed patient with persistent diarrhea
A 29-year-old lung transplant recipient presents with diarrhea lasting 1 month.
Review
- Perioperative management of pregnant women undergoing nonobstetric surgery
If surgery during pregnancy is unavoidable, special management considerations apply.
Current Drug Therapy
- Prescribing testosterone and DHEA: The role of androgens in women
Androgens play an important physiologic role and can promote sexual health.
Editorial
- Trials and tribulations of testosterone therapy in women: Importance of adhering to the evidence
Testosterone should not be touted for outcomes that are not supported by data.
Current Drug Therapy
- The role of SGLT-2 inhibitors in managing type 2 diabetes
These drugs improve glycemic control and offer cardiovascular and metabolic benefits.
Editorial
- SGLT-2 inhibitors: A new era in managing diabetic kidney disease starts now
Randomized controlled trials of these new agents had positive outcomes.
Commentary
No one in their right mind would want to return to the “good old days.”
Cleveland Clinic is 100 years old and has had a medical journal for 90 of those years.
We advocate PSA screening for all middle-aged men, especially if they have risk factors.