Table of Contents

March 01, 2023; Volume 90,Issue 3

From the Editor

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Viruses change; we can, too
Brian F. Mandell, MD, PhD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 135-136; DOI: https://doi.org/10.3949/ccjm.90b.03023

As we learn more about the mpox (formerly monkeypox) virus, Sossai et al in this issue of the Journal discuss how our understanding of its link to variola has led to therapeutic and prophylactic vaccination options.

Review

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Smallpox and monkeypox: Looking back and looking ahead
Paolo Sossai, MD, PhD, Domenico Staiti, MD, Massimiliano Cannas, MD and Piero Grima, MD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 141-144; DOI: https://doi.org/10.3949/ccjm.90a.22067

Two vaccines have been developed for mpox prevention, but clarity is needed on when and how to use them.

The Clinical Picture

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Mass under the lip
Sagar Khanna, BDS, DDS

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 145-146; DOI: https://doi.org/10.3949/ccjm.90a.22053

The mass had grown slowly over several weeks while the patient was in rehabilitation after a stroke.

1-Minute Consult

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What is the rationale for the laboratory workup for suspected pheochromocytomas and paragangliomas?
Hiba Z. Hashmi, MD, Muhammad Arslan Arif Maan, MD and Laura LaFave, MD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 150-153; DOI: https://doi.org/10.3949/ccjm.90a.20197

The decision to test is best guided by clinical suspicion. Test results should be interpreted with careful consideration of how the samples were collected.
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Fundic gland polyps: Should my patient stop taking PPIs?
Jiafei (Carolyn) Niu, DO and Yi Qin, MD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 157-160; DOI: https://doi.org/10.3949/ccjm.90a.22058

Of the 2 types of these polyps, the sporadic type is linked to proton pump inhibitor use, whereas the syndromic type occurs on a background of familial adenomatous polyposis—a key distinction.

Commentary

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The cost of ‘free’: Advising patients about sponsored genetic testing
Stephanie Allison Larson, PhD, HEC-C, Joseph Liu, MS, David Flannery, MD, Marsha Michie, PhD and Paul J. Ford, PhD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 161-164; DOI: https://doi.org/10.3949/ccjm.90a.22010

A breakdown of benefits and drawbacks of sponsored genetic testing that clinicians can use to help patients make informed decisions.

Review

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Colovesical fistula in men with chronic urinary tract infection: A diagnostic challenge
Risheng Xu, DO, Austin Vaughan, DO, Mitchell Fagan, DO, Dylan P. Schumacher, MD, Verra Wekullo, MD and Bruce Gehrke, MD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 165-171; DOI: https://doi.org/10.3949/ccjm.90a.21060

Most cases are in older men with diverticular disease, Crohn disease, cancer, or iatrogenic injury. Suspect it especially in these patients with UTI symptoms refractory to conventional treatments.
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To repeat or not to repeat? Measuring bone mineral density during anti-resorptive therapy or a drug holiday
Tayyab S. Khan, MD, Partha Sinha, MD, PhD and Harold Rosen, MD

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 173-180; DOI: https://doi.org/10.3949/ccjm.90a.22071

The authors present evidence for and against monitoring bone mineral density in these patients, arguing against a one-size-fits-all approach.

Current Drug Therapy

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Update on current contraceptive options: A case-based discussion of efficacy, eligibility, and use
Alexa Nicole Fiffick, DO, MBS, NCMP, Tara K. Iyer, MD, NCMP, Tiffany Cochran, MD, MA, NCMP and Pelin Batur, MD, FACP, NCMP

Cleveland Clinic Journal of Medicine March 2023, 90 (3) 181-190; DOI: https://doi.org/10.3949/ccjm.90a.22075

Rates of unintended pregnancy are high in the United States. Clinicians need to be well-informed about the full spectrum of contraceptive options to improve reproductive autonomy.