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Cleveland Clinic Journal of Medicine

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Table of Contents

February 01, 2023; Volume 90,Issue 2

From the Editor

  • You have access
    Myasthenia gravis: An update for internists
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 72-73; DOI: https://doi.org/10.3949/ccjm.90b.02023

    Recognizing the spectrum of the disease in patients’ complaints enhances our clinical reasoning skills when faced with the extremely commonly expressed symptom of “fatigue.”

The Clinical Picture

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    Oral leukoplakia and oral cancer
    Takeshi Onda, DDS, PhD, Kamichika Hayashi, DDS, PhD, Akira Katakura, DDS, PhD and Masayuki Takano, DDS, PhD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 79-80; DOI: https://doi.org/10.3949/ccjm.90a.22044

    A 53-year-old male who had smoked for 36 years was referred by his dentist for worsening vitiligo diagnosed as leukoplakia 3 years earlier.

1-Minute Consult

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    What are the treatment options for myasthenia gravis if first-line agents fail?
    Christopher Zust, MD and John A. Morren, MD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 81-84; DOI: https://doi.org/10.3949/ccjm.90a.22022

    From 5% to 20% of patients may have a suboptimal response or prohibitive adverse effects over a period of a few weeks to 3 months.

Commentary

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    The constellation of vitamin D, the acute-phase response, and inflammation
    Maria J. Antonelli, MD, Irving Kushner, MD and Murray Epstein, MD, FASN, FACP
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 85-89; DOI: https://doi.org/10.3949/ccjm.90a.22048

    An astronomic increase in vitamin D testing and supplementation is happening in the absence of an evidence-based rationale.

Editorial

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    Vitamin D: A metabolic bone disease perspective
    Bruce Long, MD, FACR, BS Pharm
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 91-92; DOI: https://doi.org/10.3949/ccjm.90a.22086

    When checking levels, clinicians should keep in mind that vitamin D levels fluctuate by season and time of day, and that different laboratories may use different assays that yield different results.

Symptoms to Diagnosis

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    A 50-year-old man presents with shortness of breath
    Kaylee Watson, MD, David Wolinsky, MD, Mauricio Velez, MD and David Snipelisky, MD, FACC
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 95-101; DOI: https://doi.org/10.3949/ccjm.90a.22021

    Red flags included low voltage, normal sinus rhythm, and Q waves on electrocardiography, a history of carpal tunnel syndrome, and evidence of renal dysfunction.

Review

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    Myasthenia gravis: Frequently asked questions
    John A. Morren, MD and Yuebing Li, MD, PhD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 103-113; DOI: https://doi.org/10.3949/ccjm.90a.22017

    Who is at risk? Which tests should be ordered? How does the disease course affect management decisions? What instructions should you give patients? And other questions.

  • Resistant hypertension: A stepwise approach
    You have access
    Resistant hypertension: A stepwise approach
    CME article
    Jordana Yahr, DO, George Thomas, MD, Juan Calle, MD and Jonathan J. Taliercio, DO
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 115-125; DOI: https://doi.org/10.3949/ccjm.90a.22046

    The authors review the definition and prevalence of resistant hypertension and its diagnostic workup and management, including lifestyle modifications, drugs, and experimental therapies.

2022 Reviewers

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    Our Peer-Reviewers For 2022
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine February 2023, 90 (2) 78;
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In this issue

Cleveland Clinic Journal of Medicine: 90 (2)
Cleveland Clinic Journal of Medicine
Vol. 90, Issue 2
1 Feb 2023
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Complete Issue (PDF)

Issue highlights

  • What are the treatment options for myasthenia gravis if first-line agents fail?
  • Vitamin D: A metabolic bone disease perspective
  • Resistant hypertension: A stepwise approach
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Mass under the lip
Fundic gland polyps: Should my patient stop taking PPIs?
Colovesical fistula in men with chronic urinary tract infection: A diagnostic challenge
Oral leukoplakia and oral cancer
A 50-year-old man presents with shortness of breath
Myasthenia gravis: Frequently asked questions
Central vision loss in a 44-year-old woman
Median rhomboid glossitis caused by tongue-brushing
Making best use of bone turnover markers to monitor oral bisphosphonate therapy
Asymptomatic granules on the buccal mucosa
Does my patient need to be screened or treated for a urinary tract infection?
Ignore e-cigarettes at your patient’s peril
Spontaneous oral hematoma diagnosed as angina bullosa hemorrhagica
Hypophosphatemia in a patient with an eating disorder

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