Table of Contents
From the Editor
- Aspirin in primary prevention of cardiovascular events: Key questions remain
Are we done with the issue of aspirin in primary prevention? Not quite yet.
The Clinical Picture
- Chondrodermatitis nodularis helicis
The patient first noted the mildly tender, nonpruritic lesion on his left ear after he began sleeping on a firmer pillow.
- Cholesteatoma
The patient’s audiogram showed left-sided conductive hearing loss, and examination revealed an atelectatic tympanic membrane on the left with a retraction pocket and keratin debris.
1-Minute Consult
- Should my elderly hospitalized patient with acute onset of altered mental status undergo stat head CT?
Clinical acumen and use of delirium scoring tools help narrow the range of possible causes for the individual patient and guide decisions on the need for further testing and imaging.
Guidelines to Practice
- Aspirin for primary prevention of cardiovascular disease: What do the current USPSTF guidelines say?
A concise overview of the US Preventive Services Task Force recommendations.
1-Minute Consult
- What is the optimal approach to infiltration and extravasation of nonchemotherapy medications?
The immediate response is warm or cold compression and assessment of the severity.
Review
Endocrinopathies from checkpoint inhibitors: Incidence, outcomes, and managementA review of the incidence and severity of each immune checkpoint inhibitor-related endocrinopathy, factors related to toxicity risk, and principles of management.
Editorial
- Reincarnating autoimmunity: Immune-related adverse events as new diseases
The range of adverse events is broad. Any organ can be affected, and any naturally occurring autoimmune process can be mimicked by the massive inflammation generated by checkpoint inhibition.
Commentary
The author presents scenarios illustrating the overlapping clinical manifestations of respiratory viral infections that challenge clinical diagnosis.