ABSTRACT
How to manage a patient who has an elevated serum creatine kinase (CK) level but no or insignificant muscle-related signs and symptoms is a clinical conundrum. The authors provide a systematic approach, including repeat testing after a period of rest, defining higher thresholds over which pursuing a diagnosis is worthwhile, and evaluating for a variety of nonneuromuscular causes. They also outline a workup for neuromuscular causes.
- Copyright © 2016 The Cleveland Clinic Foundation. All Rights Reserved.
- Siamak Moghadam-Kia, MD
- Chester V. Oddis, MD
- Rohit Aggarwal, MD, MS⇑
- Associate Professor of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA
- ADDRESS:
Rohit Aggarwal, MD, MS, Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, 3601 5th Avenue, Suite 2B, Pittsburgh, PA 15261; e-mail: aggarwalr{at}upmc.edu
ABSTRACT
How to manage a patient who has an elevated serum creatine kinase (CK) level but no or insignificant muscle-related signs and symptoms is a clinical conundrum. The authors provide a systematic approach, including repeat testing after a period of rest, defining higher thresholds over which pursuing a diagnosis is worthwhile, and evaluating for a variety of nonneuromuscular causes. They also outline a workup for neuromuscular causes.
- Copyright © 2016 The Cleveland Clinic Foundation. All Rights Reserved.
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