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Review

GERD: A practical approach

Andrew Young, DO, Mythri Anil Kumar, MD and Prashanthi N. Thota, MD, FACG
Cleveland Clinic Journal of Medicine April 2020, 87 (4) 223-230; DOI: https://doi.org/10.3949/ccjm.87a.19114
Andrew Young
Department of Internal Medicine, Cleveland Clinic
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Mythri Anil Kumar
Department of Gastroenterology and Hepatology, Cleveland Clinic
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Prashanthi N. Thota
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ABSTRACT

Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies taken to rule out eosinophilic esophagitis. This review discusses the evidence for different medical, endoscopic, and surgical therapies and presents a management algorithm.

  • Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.
View Full Text
  1. Andrew Young, DO
  1. Department of Internal Medicine, Cleveland Clinic
  1. Mythri Anil Kumar, MD
  1. Department of Gastroenterology and Hepatology, Cleveland Clinic
  1. Prashanthi N. Thota, MD, FACG⇑
  1. Medical Director, Esophageal Center, Digestive Disease and Surgery Institute, Cleveland Clinic
  2. Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
  1. ADDRESS:
    Prashanthi N. Thota, MD, FACG, Esophageal Center, Digestive Disease and Surgery Institute, A31, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; thotap{at}ccf.org

ABSTRACT

Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies taken to rule out eosinophilic esophagitis. This review discusses the evidence for different medical, endoscopic, and surgical therapies and presents a management algorithm.

  • Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.
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Cleveland Clinic Journal of Medicine: 87 (4)
Cleveland Clinic Journal of Medicine
Vol. 87, Issue 4
1 Apr 2020
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GERD: A practical approach
Andrew Young, Mythri Anil Kumar, Prashanthi N. Thota
Cleveland Clinic Journal of Medicine Apr 2020, 87 (4) 223-230; DOI: 10.3949/ccjm.87a.19114

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GERD: A practical approach
Andrew Young, Mythri Anil Kumar, Prashanthi N. Thota
Cleveland Clinic Journal of Medicine Apr 2020, 87 (4) 223-230; DOI: 10.3949/ccjm.87a.19114
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    • TREATMENT: LIFESTYLE, DRUG THERAPY, SURGERY
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