Obesity

  • Born again: The many lives of metformin
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 523-524; DOI: https://doi.org/10.3949/ccjm.90b.09023

    Repurposing old drugs for new indications is not a new drug-development strategy.

  • Should I consider metformin therapy for weight loss in patients with obesity but without diabetes?
    Paloma Rodriguez, MD, Kevin M. Pantalone, DO, ECNU, FACE, Marcio L. Griebeler, MD and Bartolome Burguera, MD, PhD
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 545-548; DOI: https://doi.org/10.3949/ccjm.90a.22096

    The authors appraise the evidence to date for weight loss with metformin in this patient population.

  • Antiobesity drug therapy
    Taher Modarressi, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 657; DOI: https://doi.org/10.3949/ccjm.88c.12001
  • Physician resistance to obesity pharmacotherapy
    Vania Modesto-Lowe, MD, Allison Wick, BS and Michael Dang, BS, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 658; DOI: https://doi.org/10.3949/ccjm.88c.12003
  • In Reply: Antiobesity drug therapy
    Yael Mauer, MD, MPH, Marcie Parker, PharmD, BCACP and Sangeeta Kashyap, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 657-658; DOI: https://doi.org/10.3949/ccjm.88c.12002
  • In Reply: Physician resistance to obesity pharmacotherapy
    Yael Mauer, MD, MPH, Marcie Parker, PharmD, BCACP and Sangeeta Kashyap, MD
    Cleveland Clinic Journal of Medicine December 2021, 88 (12) 658-659; DOI: https://doi.org/10.3949/ccjm.88c.12004
  • Antiobesity drug therapy: An individualized and comprehensive approach
    Yael Mauer, MD, MPH, Marcie Parker, PharmD, BCACP and Sangeeta R. Kashyap, MD
    Cleveland Clinic Journal of Medicine August 2021, 88 (8) 440-448; DOI: https://doi.org/10.3949/ccjm.88a.20080

    As part of a comprehensive plan, these drugs can provide lasting obesity control and additional health benefits, including decreased cardiovascular risk.

  • The obesity paradox in heart failure: What is the role of cardiorespiratory fitness?
    Asad Khan, MD, Erik H. Van Iterson, PhD and Luke J. Laffin, MD
    Cleveland Clinic Journal of Medicine August 2021, 88 (8) 449-458; DOI: https://doi.org/10.3949/ccjm.88a.20098

    What should these patients be advised about weight management and about cardiorespiratory fitness, a major factor influencing the paradox?

  • Promoting physical activity in older women to maximize health
    Augustine Chavez, MD, Robert Scales, PhD and Juliana M. Kling, MD, MPH
    Cleveland Clinic Journal of Medicine July 2021, 88 (7) 405-415; DOI: https://doi.org/10.3949/ccjm.88a.20170

    The optimal type, intensity, and level required to achieve specific health outcomes depend on the disease the patient and clinician are trying to prevent or manage.

  • Medical complications of bulimia nervosa
    Allison Nitsch, MD, Heather Dlugosz, MD, Dennis Gibson, MD and Philip S. Mehler, MD, FACP, FAED
    Cleveland Clinic Journal of Medicine June 2021, 88 (6) 333-343; DOI: https://doi.org/10.3949/ccjm.88a.20168

    Complications can affect all body systems, but especially the renal and electrolyte systems.

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