Obesity

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    Polycystic ovary syndrome: An update on diagnosis and management

    Nayoung Sung, MD, MSCP, Jawaria Amir, MD, Ula Abed Alwahab, MD and Tommaso Falcone, MD
    • Cleveland Clinic Journal of Medicine March 2026, 93 (3) 176-183;
    • DOI: https://doi.org/10.3949/ccjm.93a.25090

    • Because this syndrome affects health throughout the lifespan, long-term management is essential, not only to control symptoms but also to prevent associated metabolic conditions.

  • Atrial fibrillation in patients with obesity: How can we optimize management?

    Asim Kichloo, MD, Ivan Magallanes Marrufo, MPH and Suhaib Andrabi, MD
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 17-20;
    • DOI: https://doi.org/10.3949/ccjm.93a.25032

    • Heart rate and rhythm control therapies often must be adjusted when treating patients with obesity, while other measures can reduce the onset or recurrence of atrial fibrillation.

  • Update on antiobesity pharmacotherapy in adults: Current and emerging options

    Farah Ziyadeh, MD, Sara Saliba, MD, RD, Dania Salih Bacha, MD, Yael Mauer, MD, MPH, Marcio L. Griebeler, MD, DABOM and Bartolome Burguera, MD, PhD
    • Cleveland Clinic Journal of Medicine January 2026, 93 (1) 36-46;
    • DOI: https://doi.org/10.3949/ccjm.93a.24112

    • The authors review antiobesity medications that are currently available or under investigation and discuss how to personalize obesity treatment.

  • Managing obesity in older adults

    CME Image
    Shyam Sundaresh, MD, Sara Saliba, MD, RD, Farah Ziyadeh, MD, Yael Mauer, MD, MPH and Willy Marcos Valencia, MD, MSc
    • Cleveland Clinic Journal of Medicine November 2025, 92 (11) 686-692;
    • DOI: https://doi.org/10.3949/ccjm.92a.24094

    • The goals of treating obesity in older adults are to ease its complications and improve functional status and quality of life, with or without weight loss.

  • Effective but inaccessible antiobesity medications

    Sima Saberi, MD, Sabiha M. Hussain, MD, Mohammad Kazem Fallahzadeh, MD, MAS, Hector Madariaga, MD, Pooja Budhiraja, MBBS and Kenneth J. Woodside, MD
    • Cleveland Clinic Journal of Medicine March 2025, 92 (3) 141;
    • DOI: https://doi.org/10.3949/ccjm.92c.03001

  • Hypoglycemia after bariatric surgery: Management updates

    Anira Iqbal, MD and Vinni Makin, MBBS, MD
    • Cleveland Clinic Journal of Medicine February 2025, 92 (2) 103-108;
    • DOI: https://doi.org/10.3949/ccjm.92a.24033

    • The authors discuss how to differentiate post-bariatric surgery hypoglycemia from other causes of hypoglycemia, highlight the evolving role of continuous glucose monitors in detecting it, and summarize management options.

  • Effective but inaccessible antiobesity medications: A call for sharing responsibility for improving access to evidence-based care

    Bartolome Burguera, MD, PhD, Marcio L. Griebeler, MD and W. Timothy Garvey, MD
    • Cleveland Clinic Journal of Medicine November 2024, 91 (11) 671-676;
    • DOI: https://doi.org/10.3949/ccjm.91a.24068

    • The potentially transformative benefits of second-generation obesity medications have yet to be realized because many patients lack access to these medications.

  • Should I consider metformin therapy for weight loss in patients with obesity but without diabetes?

    Paloma Rodriguez, MD, Kevin M. Pantalone, DO, ECNU, FACE, Marcio L. Griebeler, MD and Bartolome Burguera, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2023, 90 (9) 545-548;
    • DOI: https://doi.org/10.3949/ccjm.90a.22096

    • The authors appraise the evidence to date for weight loss with metformin in this patient population.

  • Born again: The many lives of metformin

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2023, 90 (9) 523-524;
    • DOI: https://doi.org/10.3949/ccjm.90b.09023

    • Repurposing old drugs for new indications is not a new drug-development strategy.

  • Physician resistance to obesity pharmacotherapy

    Vania Modesto-Lowe, MD, Allison Wick, BS and Michael Dang, BS, MD
    • Cleveland Clinic Journal of Medicine December 2021, 88 (12) 658;
    • DOI: https://doi.org/10.3949/ccjm.88c.12003
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