Geriatrics
- Bone turnover markers to monitor oral bisphosphonate therapy
Rapid changes in levels of bone turnover markers can be useful in monitoring the effectiveness of therapy and improving adherence to therapy.
- Making best use of bone turnover markers to monitor oral bisphosphonate therapy
Clinical applications of bone turnover markers can include determining when to start or end a bisphosphonate “holiday” and measuring treatment response.
- Geriatric update 2022: Preventing Alzheimer disease and more
Key topics include Alzheimer dementia, effects of frailty and social isolation, COVID-19 risks in patients with dementia, hospital-at-home programs, deprescribing antihypertensive drugs, bisphosphonate-related fractures, and cannabis use.
- Managing stage 1 hypertension: Consider the risks, stop the progression
Guidelines on managing patients with stage 1 hypertension and a low 10-year risk of atherosclerotic cardiovascular disease.
- Palliative care: An update for internists
A review of recent research to guide symptom management, advance-care planning, and communication training to maximize compassionate care.
- Treating anemia: It’s not just the EPO
Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.
- Anemia of chronic kidney disease: Will new agents deliver on their promise?
A review of the pathophysiology of anemia of chronic kidney disease, major clinical trials, and novel therapies.
- Potential systemic benefits of shocking or blocking nerves
What has really caught my attention is the expanding research on controlled regional neuromodulation and its impact on systemic physiology and inflammation.
- Stellate ganglion block as a treatment for vasomotor symptoms: Clinical application
Hormone therapy is the mainstay of treatment, but there is a clear need for safe and effective nonhormonal options. The authors review data on the use of stellate ganglion block in perimenopausal and postmenopausal patients.
- Hypercalcemia and vitamin A: A vitamin to keep in mind
Vitamin A toxicity can affect bone resorption and hypercalcemia and should be explored in unexplained cases of parathyroid hormone-independent hypercalcemia.