Table of Contents
From the Editor
- The search for precision
The day may come soon when we get EMR alerts if we try to prescribe certain drugs to patients with certain gene variants.
The Clinical Picture
- A young man with hypertension and hypokalemia
At presentation, his blood pressure was 184/154 mm Hg, and his serum potassium level was 3.1 mmol/L.
- Sigmoid volvulus: Coffee bean sign, whirl sign
A 79-year-old man with cortical cerebellar atrophy presented with progressive abdominal distention and constipation.
Symptoms to Diagnosis
- A cough that won’t go away: Evaluation and treatment in 2 patients
Two patients present with similar symptoms, but different causes and treatment.
Review
- Pharmacogenomics: An evolving clinical tool for precision medicine
More than 90% of patients are thought to carry at least 1 genetic variant that should prompt a change in dosing or medication.
- Type of diabetes mellitus: Does it matter to the clinician?
Understanding the many faces of diabetes can make a difference in how clinicians select glucose-lowering therapy.
Familial hypercholesterolemia: Detect, treat, and ask about familyPatients can develop elevated LDL-C and atherosclerotic cardiovascular disease at a young age.
Letters to the Editor
Correction
- Correction
The article, “Fever in a traveler returning from Ethiopia,” by Ken Koon Wong, MD (Cleve Clin J Med 2020; 87(1):31–42; doi:10.3949/ccjm.87a.19017) contained an error in Table 7.
