ABSTRACT
Biologic therapies have become widely used but often cause cutaneous adverse effects. The authors discuss the cutaneous adverse effects of tumor necrosis factor (TNF) alpha inhibitors, epidermal growth factor receptor (EGFR) inhibitors, small-molecule tyrosine kinase inhibitors (TKIs), and cell surface-targeted monoclonal antibodies, including how to manage these reactions and when to refer to a dermatologist.
Footnotes
Dr. Fernandez has disclosed financial relationships (consulting, membership on advisory committee or review panels, research, independent contracting, or teaching and speaking) with commercial interests (Abbview Pharmaceuticals, Corbus Pharmaceuticals, Mallinckrodt, Novartis, Pfizer, and UCB).
- Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.
- Selena R. Pasadyn, BA
- Anthony P. Fernandez, MD, PhD
- Co-Medical Director of Continuing Medical Education; W.D. Steck Chair of Clinical Dermatology; Director of Medical and Inpatient Dermatology; Departments of Dermatology and Pathology, Cleveland Clinic; Assistant Clinical Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
- Christine B. Warren, MD, MS⇑
- Department of Dermatology, Cleveland Clinic; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
- Address:
Christine B. Warren, MD, MS, Department of Dermatology, A61, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195; warrenc{at}ccf.org
ABSTRACT
Biologic therapies have become widely used but often cause cutaneous adverse effects. The authors discuss the cutaneous adverse effects of tumor necrosis factor (TNF) alpha inhibitors, epidermal growth factor receptor (EGFR) inhibitors, small-molecule tyrosine kinase inhibitors (TKIs), and cell surface-targeted monoclonal antibodies, including how to manage these reactions and when to refer to a dermatologist.
Footnotes
Dr. Fernandez has disclosed financial relationships (consulting, membership on advisory committee or review panels, research, independent contracting, or teaching and speaking) with commercial interests (Abbview Pharmaceuticals, Corbus Pharmaceuticals, Mallinckrodt, Novartis, Pfizer, and UCB).
- Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.