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Review

Point-of-care ultrasonography for the hospitalist

Guramrinder Singh Thind, MD, Steven Fox, MD, Mohit Gupta, MD, Praveen Chahar, MD, Robert Jones, DO, FACEP and Siddharth Dugar, MD
Cleveland Clinic Journal of Medicine June 2021, 88 (6) 345-359; DOI: https://doi.org/10.3949/ccjm.88a.20141
Guramrinder Singh Thind
Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH
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  • For correspondence: [email protected]
Steven Fox
Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH
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Mohit Gupta
Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Praveen Chahar
Anesthesiology Institute, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Robert Jones
Department of Emergency Medicine, Metro-Health Medical Center, Cleveland, OH; Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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Siddharth Dugar
Department of Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH; Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH
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  • Figure 1
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    Figure 1

    A lines. The A-line pattern occurs in normal lung and in pneumothorax. Ultrasound waves (arrows) reflect off the pleural interface repeatedly, producing repeated horizontal lines throughout the field.

  • Figure 2
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    Figure 2

    B lines. The B-line pattern occurs in the setting of interstitial thickening by any cause, including cardiogenic pulmonary edema, noncardiogenic pulmonary edema, interstitial fibrosis, and interstitial pneumonia/pneumonitis. It is analogous to ground-glass opacity on computed tomography. It is demonstrated by vertical lines resembling the tail of a comet and extending to the bottom of the screen. In this image, confluent B lines (arrow) indicate significant interstitial involvement.

  • Figure 3
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    Figure 3

    Small peripheral (subpleural) consolidation. This is demonstrated by a small area of lung parenchyma visualized directly beneath the pleura (arrow). This pattern is common in bacterial or viral pneumonia, including COVID-19 pneumonia.

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    Figure 4

    Pleural effusion and consolidation.

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    Figure 5

    Right lower quadrant with large ascites fluid pocket; Foley catheter in bladder.

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    Figure 6

    Ascites pocket.

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    Figure 7

    Hydronephrosis. Hypoechoic (dark) fluid (arrow) is shown extending into the renal pelvis.

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    Figure 8

    Gallbladder containing sludge, with a thickened anterior wall, in a patient with acute cholecystitis.

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    Figure 9

    Right common femoral vein deep vein thrombosis. The left image shows lack of compression of the vein with applied compression of the probe. The right image shows vein without compression.

  • Figure 10
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    Figure 10

    On ultrasonography, subcutaneous fluid is demonstrated as hypoechoic or anechoic (dark) layering within islands of subcutaneous tissue (gray). This occurs in any process leading to fluid within the subcutaneous tissue, including cellulitis and hydrostatic edema.

Tables

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    TABLE 1

    Point-of-care ultrasonography workflow compared with traditional consultative ultrasonography

    Consultative ultrasonographyPOCUS
    Decision to perform ultrasonographyPrimary clinicianPrimary clinician
    Image acquisitionSonographer
    Image interpretationSonographer
    Radiologist
    Clinical integrationRadiologist
    Primary clinician
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    TABLE 2

    Meta-analyses evaluating pleural and lung ultrasonography

    DiagnosisMeta-analysisNo. of studiesNo. of patientsPooled sensitivity95% confidence intervalPooled specificity95% confidence intervalPositive likelihood ratioNegative likelihood ratio
    Pleural effusionYousefifard et al,11 2016121,55494%88%–97%98%92%–100%53.960.06
    Acute cardiogenic pulmonary edemaMaw et al,9 201971,07594.1%81.3%– 98.3%92.4%84.2%– 96.4%12.380.06
    PneumoniaAlzahrani et al,10 2017202,51385%84%–87%93%92%–95%12.140.16
    PneumothoraxAlrajab et al,8 2013a131,51478.6%68.1%–98.1%98.4%97.3%–99.5%49.130.22
    • ↵a Included 1 study that used lung sliding sign alone, 12 studies that used lung sliding and comet tail signs, and 6 studies that included lung point in addition to the other 2 signs.

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    TABLE 3

    Characteristics of B lines based on etiologya

    Cardiogenic pulmonary edemaNoncardiogenic diffuse pulmonary interstitial edemaInterstitial pneumonia or pneumonitis (bacterial, viral, or inflammatory)Interstitial fibrosis
    DistributionDiffuse
    Usually bilateral and symmetric
    Predominant in dependent regions
    Diffuse or patchy
    Often asymmetric
    Focal or patchy
    Usually asymmetric
    Diffuse or patchy
    Variable symmetry
    Spared areasAbsentOften presentPresentOften present
    Number of B linesVariableVariableVariableVariable
    PleuraSmoothIrregularIrregularIrregular
    Subpleural consolidationsAbsentPresentPresentTypically absent
    Reduced lung slidingAbsentMay be presentMay be presentMay be present
    Pleural effusionOften presentTypically absentMay be presentTypically absent
    • ↵a Defining the terminology: diffuse = present throughout; patchy = present in many areas throughout, absent in other areas throughout; focal = present in one region but not in others; spared areas = regions of lung with A-line pattern (amid a background of B-line pattern).

  • TABLE 4
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    TABLE 5

    Estimates of central venous pressure based on inferior vena cava size and collapsibility

    Inferior vena cava sizePercent collapseEstimated central venous pressure
    ≤ 2.1 cm> 50%3 mm Hg
    ≤ 2.1 cm< 50%8 mm Hg
    > 2.1 cm> 50%8 mm Hg
    > 2.1 cm< 50%15 mm Hg
    • Based on reference 35.

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    TABLE 6

    Meta-analyses evaluating point-of-care ultrasonography for diagnosing deep vein thrombosis

    Meta-analysisNo. of studiesNo. of patientsPooled sensitivity95% confidence intervalPooled specificity95% confidence intervalPositive likelihood ratioNegative likelihood ratio
    Burnside et al,50 2008693695%87%–99%96%87%– 99%23.750.05
    Pomero et al,51 2013162,37996.1%90.6%–98.5%96.8%94.6%–98.1%30.030.04
    West et al,52 2015131,80696.5%90.1%–98.8%96.8%94.7% –98.0%30.160.04

Movies

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  • Video 1. Lung point.

  • Video 2. Normal parasternal long axis view.

  • Video 3. Reduced ejection fraction.

  • Video 4. Dilated right ventricle.

  • Video 5. Pericardial effusion and tamponade.

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Cleveland Clinic Journal of Medicine: 88 (6)
Cleveland Clinic Journal of Medicine
Vol. 88, Issue 6
1 Jun 2021
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Point-of-care ultrasonography for the hospitalist
Guramrinder Singh Thind, Steven Fox, Mohit Gupta, Praveen Chahar, Robert Jones, Siddharth Dugar
Cleveland Clinic Journal of Medicine Jun 2021, 88 (6) 345-359; DOI: 10.3949/ccjm.88a.20141

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Point-of-care ultrasonography for the hospitalist
Guramrinder Singh Thind, Steven Fox, Mohit Gupta, Praveen Chahar, Robert Jones, Siddharth Dugar
Cleveland Clinic Journal of Medicine Jun 2021, 88 (6) 345-359; DOI: 10.3949/ccjm.88a.20141
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  • Article
    • ABSTRACT
    • DIRECT CLINICIAN INVOLVEMENT
    • IMPROPER USE AND INTERPRETATION CAN CAUSE HARM
    • LUNG AND PLEURAL ULTRASONOGRAPHY
    • FOCUSED CARDIAC ULTRASONOGRAPHY
    • ABDOMINAL ULTRASONOGRAPHY
    • EVALUATION OF LOWER-EXTREMITY DEEP VEIN THROMBOSIS
    • EVALUATING SKIN AND SOFT-TISSUE INFECTIONS
    • ULTRASONOGRAPHY FOR PROCEDURAL GUIDANCE
    • CONCLUSION
    • DISCLOSURES
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