Article Figures & Data
Tables
Physical activity Bodily movement from skeletal muscle contraction resulting in energy expenditure above baseline. Exercise Planned, structured, repetitive physical activity performed to improve health or fitness. MET (metabolic equivalent of task) A measure of energy expenditure for an activity with a reference of 1 MET being rest. Intensity Low intensity:
Nonsedentary activity ≤ 3 METsLeisurely walking (≤ 2 mph)
Light household choresModerate intensity: 3–5.9 METs Golfing (walking, carrying bag)
Dance
Pickleball
Brisk walk (2.5–4 mph)
Gardening
Playing with grandchildrenVigorous intensity:
≥ 6 METsHiking
Swimming
Water aerobics
Fast walk (≥ 4.5 mph)
Stationary cycling
Strenuous fitness classesActivity level Inactive: No moderate to vigorous physical activity Low: Almost completely inactive Moderate: Some physical activity >4 hr/wk or about 12 MET hr/week or more Brisk walk 4 hr/wk
Pickleball 2.5 hr/wk
Golfing (walking, with bag) 3 hr/wkHigh: Vigorous activity >3 hr/week or about 18 MET hr/wk or more Hiking 3 hr/wk
Swimming 2.5 hr/wk
Strenuous fitness class 2.5 hr/wkTypes of exercise Aerobic: Rhythmic movement of large muscles for sustained periods of time Walking
Swimming
Stationary cyclingResistance: Activity that increases skeletal muscle strength, power, endurance and mass Lifting weights
Using resistance bands
Body movement underwaterCombined: Activity with aerobic and resistance components Fitness classes with weights
Circuit trainingAdapted from reference 2.
CONDITION INTERVENTION END POINT COMPARATOR GROUP EFFECT SIZE (95% CI) CVD 7.5–14.9 MET hr/wk LTPA7 All-cause mortality No LTPA HR 0.68 (0.66–0.69) 150 min/wk MVPA8 CHD incidence No LTPA RR 0.86 (0.77–0.96) Stroke High PA3 Stroke incidence Low level PA RR 0.76 (0.64–0.89) HTN High PA4 HTN incidence Low level PA RR 0.81 (0.76–0.85) Moderate PA4 HTN incidence Low level PA RR 0.89 (0.85–0.94) Any exercise (exercise in general)14 SBP reduction Control −8.96 mm Hg (−10.27 to −7.64) Diabetes 150 min/week MVPA5 Type 2 DM incidence Inactivity RR 0.74 (0.69–0.80) Supervised aerobic exercise9 HbA1c reduction No exercise −0.30 (−0.60 to −0.45) Supervised resistance exercise9 HbA1c reduction No exercise −0.30 (−0.38 to −0.15) Combined exercise9 HbA1c reduction No exercise −0.53 (−0.68 to −0.45) Breast cancer High-level MVPA10 Breast cancer incidence Low level PA HR 0.90 (0.87–0.93) Cancerb Supervised exercise11 Health-related QOL Control SMD 0.48 (0.16–0.81) Cognitive decline Physical activity15 Alzheimer disease incidence Inactivity RR 0.61 (0.52–0.73) Moderate to high-intensity aerobic exercise16 Global cognition Control SMD 0.60 (0.21–0.98) COPD Pulmonary rehabilitation17 Dyspnea Usual care MD 0.79 (0.56–1.03) Depression Moderate to high intensity combined exercise18 Depression severityc Control SMD −0.34 (−0.52 to −0.17) Hip OA Land-based exercise12 Pain (3–6 mo) No exercise SMD −0.38 (−0.58 to −0.18) Land-based exercise12 Physical function No exercise SMD −0.37 (−0.57 to −0.16) Knee OA Land-based exercise13 Pain No exercise SMD −0.49 (−0.39 to −0.59) Land-based exercise13 Physical function No exercise SMD −0.52 (−0.39 to −0.64) Falls Exercise19 Number of fallers Control RR 0.85 (0.81–0.89) Exercise19 Falls Control RaR 0.77 (0.71–0.83) Osteoporosis Combined exercise21 Lumbar spine bone density Usual care SMD 0.349 (0.064–0.634) Exercise20 Overall fracture No exercise RR 0.49 (0.31–0.76) ↵a Most studies cited here included both men and women.
↵b Breast, colorectal, head and neck, lymphoma, others.
↵c Severity determined by self-report on depression scales.
CHD = congestive heart disease; COPD = chronic obstructive pulmonary disease; CVD = cardiovascular disease; DM = diabetes mellitus; HbA1c = hemoglobin A1c; HR = hazard ratio; HTN = hypertension; LTPA = leisure-time physical activity; MD = mean difference; MET = metabolic equivalent of task; MVPA = moderate to vigorous physical activity; OA = osteoarthritis; PA = physical activity; QOL = quality of life; RaR = rate ratio; RR = relative risk; SBP = systolic blood pressure; SMD = standard mean difference