Pain

  • Vertebral fractures after denosumab cessation
    Jolan Dupont, MD, Michaël R. Laurent, MD,PhD, Lenore Dedeyne, MSc, Frank P. Luyten, MD,PhD, Evelien Gielen, MD,PhD and Marian Dejaeger, MD,PhD
    Cleveland Clinic Journal of Medicine June 2020, 87 (6) 337-338; DOI: https://doi.org/10.3949/ccjm.87a.19152

    The patient had a 6-month history of lumbar and dorsal back pain, initially suspected to be facet arthrosis.

  • Denosumab cessation
    Chad L. Deal, MD
    Cleveland Clinic Journal of Medicine June 2020, 87 (6) 339-341; DOI: https://doi.org/10.3949/ccjm.87a.20040

    Bone loss is rapid if patients miss injections. Clinicians can take extra measures to ensure patients get appropriate treatment.

  • Endoscopic ultrasonography: An inside view
    Endoscopic ultrasonography: An inside view
    C. Roberto Simons-Linares, MD, Praneet Wander, MD, John Vargo, MD and Prabhleen Chahal, MD
    Cleveland Clinic Journal of Medicine March 2020, 87 (3) 175-183; DOI: https://doi.org/10.3949/ccjm.87a.19003

    Endoscopic ultrasonography has evolved from a diagnostic tool to a therapeutic procedure for a wide range of conditions.

  • Pharmacogenomics: An evolving clinical tool for precision medicine
    Jennifer K. Hockings, PharmD, PhD, Amy L. Pasternak, PharmD, Angelika L. Erwin, MD, PhD, Neil T. Mason, MBA, Charis Eng, MD, PhD and J. Kevin Hicks, PharmD, PhD
    Cleveland Clinic Journal of Medicine February 2020, 87 (2) 91-99; DOI: https://doi.org/10.3949/ccjm.87a.19073

    More than 90% of patients are thought to carry at least 1 genetic variant that should prompt a change in dosing or medication.

  • Off-label and oft-prescribed
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 766-767; DOI: https://doi.org/10.3949/ccjm.86b.12019

    When prescribing drugs for uses beyond their FDA indications, we need to explain their anticipated side effects and benefits.

  • Functional heartburn: An underrecognized cause of PPI-refractory symptoms
    Functional heartburn: An underrecognized cause of PPI-refractory symptoms
    Scott Gabbard, MD and Sonya Vijayvargiya,
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 799-806; DOI: https://doi.org/10.3949/ccjm.86a.19006

    Functional heartburn is the most common cause of failure of proton pump inhibitor therapy.

  • Beyond depression: Other uses for tricyclic antidepressants
    Joanne Schneider, DNP, RN, CNP, Mary Patterson, CNP and Xavier F. Jimenez, MD, MA
    Cleveland Clinic Journal of Medicine December 2019, 86 (12) 807-814; DOI: https://doi.org/10.3949/ccjm.86a.19005

    The pharmacology of these drugs, their potential uses in conditions other than depression, and safety considerations.

  • SEEDS for success: Lifestyle management in migraine
    Jennifer Robblee, MD, MSc and Amaal J. Starling, MD
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 741-749; DOI: https://doi.org/10.3949/ccjm.86a.19009

    Lifestyle counseling can be based on the mnemonic SEEDS: sleep, exercise, eat, diary, and stress.

  • A few pearls can help prepare the mind
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 638-639; DOI: https://doi.org/10.3949/ccjm.86b.10019

    The caregiver with a prepared mind is more likely to experience the diagnostic epiphany.

  • Myopathy for the general internist: Statins and much more
    Chester V. Oddis, MD
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 656-664; DOI: https://doi.org/10.3949/ccjm.86gr.19001

    How to evaluate and manage muscle complaints in patients taking a statin, interpret creatine kinase test results, and recognize common as well as potentially dangerous myopathies.

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