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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Drug Therapy

  • You have access
    ERAAs for menopause treatment: Welcome the ‘designer estrogens’
    Heather D. Hirsch, MD, MS, NCMP, Elim Shih, MD, NCMP and Holly L. Thacker, MD, NCMP
    Cleveland Clinic Journal of Medicine June 2017, 84 (6) 463-470; DOI: https://doi.org/10.3949/ccjm.84a.15140

    These drugs stimulate estrogen receptors in some tissues and inhibit them in others, enabling tailored treatment.

  • Benign prostatic hyperplasia: Evaluation and medical management in primary care
    You have access
    Benign prostatic hyperplasia: Evaluation and medical management in primary care
    Raman Unnikrishnan, MD, Nima Almassi, MD and Khaled Fareed, MD
    Cleveland Clinic Journal of Medicine January 2017, 84 (1) 53-64; DOI: https://doi.org/10.3949/ccjm.84a.16008

    Effective medical therapy is available but underutilized in the primary care setting.

  • You have access
    Delirium in hospitalized patients: Risks and benefits of antipsychotics
    Robyn Pauline Thom, MD, Clare Kelleher Mock, MD and Polina Teslyar, MD
    Cleveland Clinic Journal of Medicine August 2017, 84 (8) 616-622; DOI: https://doi.org/10.3949/ccjm.84a.16077

    No drug is approved for delirium, but antipsychotics can be used in certain situations.

  • You have access
    Combined hormonal contraceptives and migraine: An update on the evidence
    Anne H. Calhoun, MD, FAHS and Pelin Batur, MD, FACP, NCMP
    Cleveland Clinic Journal of Medicine August 2017, 84 (8) 631-638; DOI: https://doi.org/10.3949/ccjm.84a.16033

    These contraceptives are contraindicated in women who have migraine with aura, but benefit vs risk is debatable.

  • You have access
    Antibiotic stewardship: Why we must, how we can
    Arjun Srinivasan, MD, FSHEA, CAPT USPHS
    Cleveland Clinic Journal of Medicine September 2017, 84 (9) 673-679; DOI: https://doi.org/10.3949/ccjm.84gr.17003

    It has always been a good idea; now it is required.

  • You have access
    Reproductive planning for women after solid-organ transplant
    Mina Al-Badri, MBCHB, Juliana M. Kling, MD, MPH and Suneela Vegunta, MD
    Cleveland Clinic Journal of Medicine September 2017, 84 (9) 719-728; DOI: https://doi.org/10.3949/ccjm.84a.16116

    Pregnancy can succeed, but patients must wait at least a year. Until then, meticulous contraception is mandatory.

  • You have access
    Opioid therapy and sleep apnea (June 2016)
    Aaron S. Geller, MD
    Cleveland Clinic Journal of Medicine February 2017, 84 (2) 91-94; DOI: https://doi.org/10.3949/ccjm.84c.02001

    Readers comment on opioids and sleep apnea (June 2016).

  • You have access
    To have not and then to have: A challenging immune paradox
    Brian F. Mandell, MD
    Cleveland Clinic Journal of Medicine December 2017, 84 (12) 912-913; DOI: https://doi.org/10.3949/ccjm.84b.12017

    The immune reactivation syndrome can occur when the immune system in an immunosuppressed patient with a partially controlled indolent infection is suddenly normalized.

  • You have access
    Drug reaction or metastatic lung cancer?
    Hiromichi Hara, MD, PhD, Hirofumi Utsumi, MD, PhD, Hiroshi Wakui, MD, PhD, Haruhiko Yanagisawa, MD, PhD, Mitsuo Hashimoto, MD, PhD and Kazuyoshi Kuwano, MD, PhD
    Cleveland Clinic Journal of Medicine December 2017, 84 (12) 914-915; DOI: https://doi.org/10.3949/ccjm.84a.17005

    Imaging shows nodules randomly distributed throughout both lungs, a paradoxical reaction to drug therapy.

  • Diagnosis and treatment of hyperkalemia
    You have access
    Diagnosis and treatment of hyperkalemia
    Biff F. Palmer, MD and Deborah J. Clegg, PhD
    Cleveland Clinic Journal of Medicine December 2017, 84 (12) 934-942; DOI: https://doi.org/10.3949/ccjm.84a.17056

    It is most common in patients with renal impairment, can be life-threatening, and requires a multidisciplinary approach.

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