Physical Exam

  • A historical irony—quantitative measurement in critically ill patients is not a panacea

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 575-576;
    • DOI: https://doi.org/10.3949/ccjm.93b.10026

    • Some diagnostic tools that were supposed to render the bedside examination less relevant have themselves failed the test of necessity; meanwhile, the bedside skills they supposedly would displace have also atrophied.

  • Painless sternoclavicular osteitis in fever of unknown origin: A clue to probable SAPHO syndrome

    Taisuke Kamiyoshikawa, MD, Kensaku Shojima, MD, PhD, Yoshihiro Wada, MD, PhD, Hiromitsu Yamazaki, MD, PhD, Yasuyuki Nagasawa, MD, PhD and Ken Shinmura, MD, PhD
    • Cleveland Clinic Journal of Medicine October 2026, 93 (10) 578-580;
    • DOI: https://doi.org/10.3949/ccjm.93a.25110

    • After more than 1 month of acetaminophen, the patient continued to have fever and elevated inflammatory markers.

  • A painful ulcerative lesion on the lip

    Reuben J. Arasaratnam, MD, MPH, Lenka Stankova, MD, Joseph L. Milburn, MD, Bradford T. Barker, MD, Megan B. Wachsmann, MD and Donald F. Storey, MD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 512-514;
    • DOI: https://doi.org/10.3949/ccjm.93a.26033

    • In addition to progressive ulceration of the right lower lip, the patient had a 1-year history of reduced appetite and a 20-pound weight loss.

  • Actinic keratosis: A clinician’s guide to diagnosis and treatment

    CME Image
    Taylor A. Bullock, MD, Michael Christopher, MD and Edward V. Maytin, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 541-549;
    • DOI: https://doi.org/10.3949/ccjm.93a.26005

    • Early recognition and effective treatment are key to preventing these premalignant lesions from progressing to invasive squamous cell carcinoma.

  • Lemierre syndrome (septic thrombophlebitis of the internal jugular vein)

    Daichi Yomogida, MD, Shinjiro Horikawa, MD, PhD and Yoshinao Koshida, MD, PhD
    • Cleveland Clinic Journal of Medicine September 2026, 93 (9) 510-511;
    • DOI: https://doi.org/10.3949/ccjm.93a.26012

    • The patient presented with fever and left chest pain more than 2 weeks after experiencing common cold symptoms.

  • Iatrogenic calcinosis cutis from calcium gluconate extravasation

    Fotios Vlahos, MS and Iosifina Giannakikou, MD
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 454-456;
    • DOI: https://doi.org/10.3949/ccjm.93a.25112

    • While receiving an infusion of 10% calcium gluconate, the patient developed pain, swelling, and erythema at the catheter site.

  • Mucocutaneous rash after respiratory infection

    Mandlin Abdulaziz Almousa, DMD, Narath Carlile, MD, MPH and Nathaniel Treister, DMD, DMSc
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 457-458;
    • DOI: https://doi.org/10.3949/ccjm.93a.26001

    • The patient presented with conjunctivitis, skin rash, and oral and genital mucosal lesions 2 weeks after being ill with a fever, productive cough, and myalgia.

  • Postinfectious immunologic syndromes

    Brian F. Mandell, MD, PhD
    • Cleveland Clinic Journal of Medicine August 2026, 93 (8) 447-448;
    • DOI: https://doi.org/10.3949/ccjm.93b.08026

    • Activation of the immune system can be associated with many off-target manifestations.

  • An uncommon skin manifestation after radial artery catheterization

    Zachary Meili, DO, Christopher Wilson, Mustafa Almosawi, Fares Kasem, DO and Marcus Stoddard, MD
    • Cleveland Clinic Journal of Medicine July 2026, 93 (7) 387-388;
    • DOI: https://doi.org/10.3949/ccjm.93a.25085

    • A rash developed over the dorsum of the patient’s right hand immediately after compression bands were placed over the radial arteriotomy site.

  • Iris roseola: A diagnostic clue in neurosyphilis

    Victor Alegre-Ituarte, MD, PhD and Elena Franz-Lacomba, MD
    • Cleveland Clinic Journal of Medicine May 2026, 93 (5) 259-260;
    • DOI: https://doi.org/10.3949/ccjm.93a.25047

    • The patient had a 3-week history of decreased vision in the left eye, with a best-corrected visual acuity of 20/100.

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