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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Mental Health

  • You have access
    Psychedelics in the medical toolbox?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 200-201; DOI: https://doi.org/10.3949/ccjm.92b.04025

    Given the historical association of psychedelics as “recreational” mind-altering compounds within countercultures of the 1960s and 1970s, their current introduction into several aspects of medical practice is a surprise to many.

  • You have access
    Nociplastic pain: A practical guide to chronic pain management in the primary care setting
    CME article
    Rupak Thapa, MD and Dennis Ang, MD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 236-247; DOI: https://doi.org/10.3949/ccjm.92a.24101

    Nociplastic pain is characterized by amplification of pain transmission and pain perception and does not involve visible tissue injury or damage, which makes it difficult to understand and manage.

  • You have access
    Psychedelics, spirituality, and existential distress in patients at the end of life
    Nicole Cornish, PharmD, Tara Coles, MD, M. Jennifer Cheng, MD, Claudia Ruiz Sotomayor, MD, DBe, Aaron Wolfgang, MD and Christopher Spevak, MD, MPH, JD
    Cleveland Clinic Journal of Medicine April 2025, 92 (4) 248-254; DOI: https://doi.org/10.3949/ccjm.92a.24100

    The authors explore the role of psychedelics in addressing patients’ spiritual and existential suffering at the end of life from a medical, ethical, and legal perspective.

  • You have access
    Reducing the risks when using benzodiazepines to treat insomnia: A public health approach
    Vania Modesto-Lowe, MD, MPH, Margaret M. Chaplin, MD, Roberto León-Barriera, MD and Lakshit Jain, MD
    Cleveland Clinic Journal of Medicine May 2024, 91 (5) 293-299; DOI: https://doi.org/10.3949/ccjm.91a.23061

    The authors review measures for preventing harm before benzodiazepines are prescribed, decreasing harm within 4 weeks after they are prescribed, and limiting harmful effects of long-term prescribing.

  • You have access
    A new paradigm for adult ADHD
    Uche Nkanginieme, Medical student
    Cleveland Clinic Journal of Medicine October 2023, 90 (10) 592-593; DOI: https://doi.org/10.3949/ccjm.90c.10002
  • You have access
    A new paradigm for adult ADHD
    Vania Modesto-Lowe, MD, MPH and Samantha Frigon
    Cleveland Clinic Journal of Medicine October 2023, 90 (10) 592; DOI: https://doi.org/10.3949/ccjm.90c.10001
  • You have access
    In Reply: A new paradigm for adult ADHD
    Michael J. Manos, PhD and Elizabeth J. Short, PhD
    Cleveland Clinic Journal of Medicine October 2023, 90 (10) 593; DOI: https://doi.org/10.3949/ccjm.90c.10003
  • You have access
    A practical guide for buprenorphine initiation in the primary care setting
    Roberto León-Barriera, MD, Samantha Jayne Zwiebel, MD, MA and Vania Modesto-Lowe, MD, MPH
    Cleveland Clinic Journal of Medicine September 2023, 90 (9) 557-564; DOI: https://doi.org/10.3949/ccjm.90a.23022

    The authors review changes in prescribing laws and outline buprenorphine induction protocols that can be adopted in the primary care setting.

  • You have access
    A new paradigm for adult ADHD: A focused strategy to monitor treatment
    Michael J. Manos, PhD and Elizabeth J. Short, PhD
    Cleveland Clinic Journal of Medicine July 2023, 90 (7) 413-421; DOI: https://doi.org/10.3949/ccjm.90a.22080

    In adults with attention deficit hyperactivity disorder, shifting the focus of treatment from reducing symptoms to increasing task completions can allow the physician and patient to quickly determine effectiveness of pharmacotherapy.

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    Acute anxiety and tachycardia in a hospitalized 59-year-old woman
    Andres I. Applewhite, MD, Fernando F. Stancampiano, MD, Dana M. Harris, MD, Victor Bernet, MD, Joseph G. Cernigliaro, MD and Jose R. Valery, MD
    Cleveland Clinic Journal of Medicine July 2022, 89 (7) 383-391; DOI: https://doi.org/10.3949/ccjm.89a.21002

    The patient presented with neck pain, painful swallowing, headache, and fever. She had contracted lymphoproliferative disease after liver transplant. She had stage 3 chronic kidney disease.

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