Endocrinology
- Hyperpigmentation as a clue to Addison disease
The 66-year-old woman presented with fatigue, loss of appetite, and hyperpigmentation of the tongue, soft palate, buccal mucosa, lower lip, fingers, and nail beds.
- Primary and secondary prevention of atherosclerotic cardiovascular disease: A case-based approach
The authors present commonly encountered clinical scenarios that pose challenges in decision-making in primary and secondary prevention.
- Xanthomas: Differentiating atherogenic from nonatherogenic
The patient had tendinous xanthomas on the dorsal joints of the hand and eruptive xanthomas on the buttock, as well as xanthoma striatum palmare on the volar aspect of the hand.
- The role of GLP-1 receptor agonists in managing type 2 diabetes
A review of the evidence regarding the benefits and adverse effects of GLP-1 receptor agonists in patients with type 2 diabetes mellitus or obesity.
- Acute anxiety and tachycardia in a hospitalized 59-year-old woman
The patient presented with neck pain, painful swallowing, headache, and fever. She had contracted lymphoproliferative disease after liver transplant. She had stage 3 chronic kidney disease.
- Spotty skin pigmentation in Carney complex
Characteristic skin findings and their locations can indicate underlying hereditary lentiginosis syndromes.
- Treating anemia: It’s not just the EPO
Long-term effects of treatment with the new oral inhibitors of prolyl hydroxylase will need to be carefully monitored, as prolyl hydroxylase is a key structural component of diverse proteins.
- Oral hyperpigmentation with weakness and salt-craving
The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.
- The devil is in the details: Approach to refractory hypokalemia
The authors illustrate a stepwise approach to the evaluation of acid-base disturbances.
- Glycemic targets in the ICU: A look back, and ahead
Much work is still needed to understand the nuances of glycemic targets in critically ill patients, and to learn how to take advantage of evolving technology to improve glycemic control.