Endocrinology
- LADA: A case for starting insulin therapy at diagnosis
The author discusses factors that support starting insulin therapy at diagnosis in all patients with latent autoimmune diabetes in adults.
- Lipoprotein ‘little a’: More than a little target in the management of cardiovascular risk?
Lipoprotein(a) was once believed to play no contributory role in the development of cardiovascular disease. That storyline has since flipped.
- What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.
- Lipoprotein(a) in clinical practice: What clinicians need to know
Elevated lipoprotein(a) by itself is not an indication for statin therapy, but its presence supports earlier or more aggressive preventive therapy.
- Managing obesity in older adults
The goals of treating obesity in older adults are to ease its complications and improve functional status and quality of life, with or without weight loss.
- Thyroid eye disease: What’s the latest?
A better understanding of the pathophysiology of this autoimmune disorder has led to innovative insights into its treatment, but long-term management remains a challenge.
- Teprotumumab for thyroid eye disease: A reality check
Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.

