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Cleveland Clinic Journal of Medicine
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Cleveland Clinic Journal of Medicine

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Endocrinology

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    LADA: A case for starting insulin therapy at diagnosis
    Byron J. Hoogwerf, MD
    Cleveland Clinic Journal of Medicine December 2025, 92 (12) 764-766; DOI: https://doi.org/10.3949/ccjm.92a.25084

    The author discusses factors that support starting insulin therapy at diagnosis in all patients with latent autoimmune diabetes in adults.

  • You have access
    Lipoprotein ‘little a’: More than a little target in the management of cardiovascular risk?
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 647-648; DOI: https://doi.org/10.3949/ccjm.92b.11025

    Lipoprotein(a) was once believed to play no contributory role in the development of cardiovascular disease. That storyline has since flipped.

  • You have access
    Managing noninsulin glucose-lowering medications before surgery
    Adam Kaplan, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 651; DOI: https://doi.org/10.3949/ccjm.92c.11001
  • You have access
    In Reply: Managing noninsulin glucose-lowering medications before surgery
    Oscar L. Morey-Vargas, MD, Mona Gossmann, MD, Jeffrey M. Ketz, PharmD and Basem B. Abdelmalak, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 651-652; DOI: https://doi.org/10.3949/ccjm.92c.11002
  • You have access
    What is the optimal time for bone density screening in patients with premature ovarian insufficiency?
    Dewonna Ferguson, MD, MSCP, Suneela Vegunta, MD, MSCP and Sara Shihab, MD, MSCP
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 676-678; DOI: https://doi.org/10.3949/ccjm.92a.24116

    Dual-energy x-ray absorptiometry should be performed at diagnosis, with the timing of repeat scans predicated on the patient’s clinical risk factors for fracture.

  • Lipoprotein(a) in clinical practice: What clinicians need to know
    You have access
    Lipoprotein(a) in clinical practice: What clinicians need to know
    Astefanos Al-Dalakta, MD, Leslie S. Cho, MD and Ashish Sarraju, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 679-685; DOI: https://doi.org/10.3949/ccjm.92a.25020

    Elevated lipoprotein(a) by itself is not an indication for statin therapy, but its presence supports earlier or more aggressive preventive therapy.

  • You have access
    Managing obesity in older adults
    CME article
    Shyam Sundaresh, MD, Sara Saliba, MD, RD, Farah Ziyadeh, MD, Yael Mauer, MD, MPH and Willy Marcos Valencia, MD, MSc
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 686-692; DOI: https://doi.org/10.3949/ccjm.92a.24094

    The goals of treating obesity in older adults are to ease its complications and improve functional status and quality of life, with or without weight loss.

  • You have access
    Thyroid eye disease: What’s the latest?
    CME article
    Ashley B. Vincent, DO, Alexander R. Engelmann, MD, Catherine J. Hwang, MD and Christian Nasr, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 693-701; DOI: https://doi.org/10.3949/ccjm.92a.25043

    A better understanding of the pathophysiology of this autoimmune disorder has led to innovative insights into its treatment, but long-term management remains a challenge.

  • You have access
    Teprotumumab for thyroid eye disease: A reality check
    Julian Perry, MD
    Cleveland Clinic Journal of Medicine November 2025, 92 (11) 702-703; DOI: https://doi.org/10.3949/ccjm.92a.25066

    Initial enthusiasm for teprotumumab as therapy for thyroid eye disease has been tempered by longitudinal data suggesting that it often does not alter the natural disease course.

  • You have access
    Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce
    Cleveland Clinic Journal of Medicine October 2025, 92 (10) 593;

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