Allergy/Immunology

  • Erythematous patches with keratotic annular borders on the glans penis
    Elisabeth Gómez-Moyano, MD, PhD, Inmaculada Ureña-Garnica, MD, PhD, Sara Manrique-Arija, MD, PhD and Luis Miguel Perez-Belmonte, MD, PhD
    Cleveland Clinic Journal of Medicine January 2017, 84 (1) 23-24; DOI: https://doi.org/10.3949/ccjm.84a.15145

    Reactive arthritis was diagnosed on the basis of urethritis, ocular symptoms, circinate balanitis, and sacroiliitis.

  • Weight loss, fatigue, and renal failure
    Qiwei Paulson, MD, Christopher A. Stearns, MD and Paul Nader, MD
    Cleveland Clinic Journal of Medicine August 2017, 84 (8) 601-607; DOI: https://doi.org/10.3949/ccjm.84a.16053

    A 37-year-old man has gradually lost 100 lb over the past 2 years, with progressive fatigue and malaise.

  • To have not and then to have: A challenging immune paradox
    Brian F. Mandell, MD
    Cleveland Clinic Journal of Medicine December 2017, 84 (12) 912-913; DOI: https://doi.org/10.3949/ccjm.84b.12017

    The immune reactivation syndrome can occur when the immune system in an immunosuppressed patient with a partially controlled indolent infection is suddenly normalized.

  • Drug reaction or metastatic lung cancer?
    Hiromichi Hara, MD, PhD, Hirofumi Utsumi, MD, PhD, Hiroshi Wakui, MD, PhD, Haruhiko Yanagisawa, MD, PhD, Mitsuo Hashimoto, MD, PhD and Kazuyoshi Kuwano, MD, PhD
    Cleveland Clinic Journal of Medicine December 2017, 84 (12) 914-915; DOI: https://doi.org/10.3949/ccjm.84a.17005

    Imaging shows nodules randomly distributed throughout both lungs, a paradoxical reaction to drug therapy.

  • Trust the thyroid thermostat
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine August 2016, 83 (8) 552-553; DOI: https://doi.org/10.3949/ccjm.83b.08016

    Why do some physicians persist in regularly following the T3 and T4 levels in addition to the TSH?

  • Multiple linear subcutaneous nodules
    Gitesh U. Sawatkar, MD, Dipankar De, MD, Uma Nahar Saikia, MD and Sanjeev Handa, MD, FRCP (EDIN)
    Cleveland Clinic Journal of Medicine June 2016, 83 (6) 414-416; DOI: https://doi.org/10.3949/ccjm.83a.15058

    A 34-year-old woman has an asymptomatic swelling on her foot that has been slowly growing for 15 years.

  • Whiplash-shaped acute rash
    Lidia Maroñas-Jiménez, MD, Alejandro Lobato-Berezo, MD, Ramon Pigem, MD, Diana Menis, MD and Sara Palencia-Pérez, MD, PhD
    Cleveland Clinic Journal of Medicine June 2016, 83 (6) 417-418; DOI: https://doi.org/10.3949/ccjm.83a.15062

    The rash appeared suddenly 2 days after the patient ate Chinese food.

  • Allergen-specific IgE serologic assays define sensitization, not disease (January 2016)
    Robert G. Hamilton, PhD, DABMLI, FAAAA
    Cleveland Clinic Journal of Medicine May 2016, 83 (5) 326-327; DOI: https://doi.org/10.3949/ccjm.83c.05001

    A reader comments on serum IgE testing for allergy (January 2016).

  • Celiac disease: Managing a multisystem disorder
    Celiac disease: Managing a multisystem disorder
    Gursimran Singh Kochhar, MD, CNSC, FACP, Tavankit Singh, MD, Anant Gill, MBBS and Donald F. Kirby, MD, FACP, FACN, FACG, AGAF, CNSC, CPNS
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 217-227; DOI: https://doi.org/10.3949/ccjm.83a.14158

    This autoimmune disorder can cause symptoms that involve not only the gastrointestinal tract but also the skin and bones.

  • The microbiome in celiac disease: Beyond diet-genetic interactions
    Jose U. Scher, MD
    Cleveland Clinic Journal of Medicine March 2016, 83 (3) 228-230; DOI: https://doi.org/10.3949/ccjm.83a.15123

    Evidence points to the mix of bacteria that make the gut their home, collectively called the microbiome.

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