Drug Therapy

  • STI update: Testing, treatment, and emerging threats
    Matifadza Hlatshwayo, MD, MPH, Hilary E. L. Reno, MD, PhD and Melanie L. Yarbrough, PhD
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 733-740; DOI: https://doi.org/10.3949/ccjm.86a.18098

    Fast, sensitive molecular diagnostic tests that use self-collected samples may help bend the upward curve of STIs.

  • Diabetes management
    Cleveland Clinic Journal of Medicine November 2019, 86 (11) 760;

    Information was omitted from Table 1 on page 596 of the article, Makin V, Lansang MC. Diabetes management: Beyond hemoglobin A1c. Cleve Clin J Med 2019; 86(9):595–600. doi:10.3949/ccjm.86a.18031

  • A few pearls can help prepare the mind
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 638-639; DOI: https://doi.org/10.3949/ccjm.86b.10019

    The caregiver with a prepared mind is more likely to experience the diagnostic epiphany.

  • A complication of enoxaparin injection
    Ahmad Muneer Sharayah, MD, Samrah Zaigham, MD, Noor Hajjaj, MD and Mihir Maniar, DO
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 648-649; DOI: https://doi.org/10.3949/ccjm.86a.19026

    Computed tomography revealed a hematoma measuring 15 by 15 cm compressing the bladder and causing hydronephrosis.

  • Myopathy for the general internist: Statins and much more
    Chester V. Oddis, MD
    Cleveland Clinic Journal of Medicine October 2019, 86 (10) 656-664; DOI: https://doi.org/10.3949/ccjm.86gr.19001

    How to evaluate and manage muscle complaints in patients taking a statin, interpret creatine kinase test results, and recognize common as well as potentially dangerous myopathies.

  • Clinical outcomes in diabetes: It’s not just the glucose (and it’s not so simple)
    Brian F. Mandell, MD, PhD
    Cleveland Clinic Journal of Medicine September 2019, 86 (9) 573-574; DOI: https://doi.org/10.3949/ccjm.86b.09019

    As we dig deeper into the reduction in cardiovascular deaths seen with some newer drugs, several questions arise.

  • Pseudo-Ludwig angina
    Andrew Tiu, MD and Kamolyut Lapumnuaypol, MD
    Cleveland Clinic Journal of Medicine September 2019, 86 (9) 577-578; DOI: https://doi.org/10.3949/ccjm.86a.19014

    A woman on heparin developed a hematoma on the floor of her mouth that threatened to block her airway.

  • Mediastinal granuloma due to histoplasmosis in a patient on infliximab
    Takaaki Kobayashi, MD and Christine Cho, MD
    Cleveland Clinic Journal of Medicine September 2019, 86 (9) 579-581; DOI: https://doi.org/10.3949/ccjm.86a.18138

    Immunosuppressive drugs can predispose to invasive fungal infection.

  • Diabetes management: Beyond hemoglobin A1c
    Vinni Makin, MBBS, MD, FACE and M. Cecilia Lansang, MD, MPH
    Cleveland Clinic Journal of Medicine September 2019, 86 (9) 595-600; DOI: https://doi.org/10.3949/ccjm.86a.18031

    Other factors include cardiovascular benefit, weight control, hypoglycemia risk, and cost.

  • ACE inhibitors and ARBs: Managing potassium and renal function
    Tasnim Momoniat, MBCHB, MRCP (UK), Duha Ilyas, MBBS, MRCP (UK) and Sunil Bhandari, MBCHB, FRCP, PhD, M CLIN EDU, FHEA
    Cleveland Clinic Journal of Medicine September 2019, 86 (9) 601-607; DOI: https://doi.org/10.3949/ccjm.86a.18024

    Concern about hyperkalemia and a decline in renal function has led to underuse of these drugs.

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