Drug Therapy

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Denosumab cessation
Chad L. Deal, MD

Cleveland Clinic Journal of Medicine June 2020, 87 (6) 339-341; DOI: https://doi.org/10.3949/ccjm.87a.20040

Bone loss is rapid if patients miss injections. Clinicians can take extra measures to ensure patients get appropriate treatment.
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Is it safe to continue biologic agents during surgery in patients with inflammatory bowel disease?
Zain Moosvi, MD, Alexander Abadir, MD, Jacqueline Duong, BS and Douglas Nguyen, MD

Cleveland Clinic Journal of Medicine June 2020, 87 (6) 343-346; DOI: https://doi.org/10.3949/ccjm.87a.19071

Patients taking monoclonal antibodies can continue taking them, but small-molecule drugs should be withheld.
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Recurrent Clostridioides difficile infection: Recognition, management, prevention
Constantine Tsigrelis, MD

Cleveland Clinic Journal of Medicine June 2020, 87 (6) 347-359; DOI: https://doi.org/10.3949/ccjm.87gr.20001
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Cutaneous adverse effects of biologic medications
Selena R. Pasadyn, BA, Daniel Knabel, MD, Anthony P. Fernandez, MD, PhD and Christine B. Warren, MD, MS

Cleveland Clinic Journal of Medicine May 2020, 87 (5) 288-299; DOI: https://doi.org/10.3949/ccjm.87a.19119

These therapies have revolutionized medicine but come with many unique adverse effects.
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Aspirin for primary prevention of atherosclerotic cardiovascular events
Aldo L. Schenone, MD and A. Michael Lincoff, MD

Cleveland Clinic Journal of Medicine May 2020, 87 (5) 300-311; DOI: https://doi.org/10.3949/ccjm.87a.19045

A more limited role for aspirin as primary prevention in patients at intermediate risk, with diabetes, and the elderly.
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Familial hypercholesterolemia
Cleveland Clinic Journal of Medicine May 2020, 87 (5) 311;

The following article contained an error: Shah NP, Ahmed HM, Tang WH. Familial hypercholesterolemia: Detect, treat, and ask about family. Cleve Clin J Med 2020; 87(2):109–120. doi:10.3949/ccjm.87a.19021.
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A practical approach to the cholesterol guidelines and ASCVD prevention
Leslie Cho, MD

Cleveland Clinic Journal of Medicine May 2020, 87 (5 suppl 1) 15-20; DOI: https://doi.org/10.3949/ccjm.87.s1.02
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New treatments for peripheral artery disease
John Bartholomew, MD and G. Jay Bishop, MD

Cleveland Clinic Journal of Medicine May 2020, 87 (5 suppl 1) 21-25; DOI: https://doi.org/10.3949/ccjm.87.s1.03
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Can I use direct oral anticoagulants to treat cancer-associated venous thromboembolism?
Oluwadunni Emiloju, MD, Sorab Gupta, MD and Claudia Dourado, MD

Cleveland Clinic Journal of Medicine April 2020, 87 (4) 201-203; DOI: https://doi.org/10.3949/ccjm.87a.19100

DOACs are increasingly replacing low-molecular-weight heparins for this purpose.
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CGRP antagonists for decreasing migraine frequency: New options, long overdue
Julia Bucklan, DO and Zubair Ahmed, MD

Cleveland Clinic Journal of Medicine April 2020, 87 (4) 211-218; DOI: https://doi.org/10.3949/ccjm.87a.19048

CGRP drugs are an exciting frontier, but migraine management is still a combination of lifestyle changes plus treatment.

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