Gastroenterology
- Which ICU patients need stress ulcer prophylaxis?
An examination of the controversy surrounding stress ulcer prophylaxis in critically ill patients, with guidance for its appropriate use in this setting.
- A clinical trial and another clinical practice bites the dust, or should there not be an appendix?
Studies over the past 2 decades have assessed an alternative approach to acute appendicitis: treatment with systemic antibiotics and observation.
- Appendicitis management: Is it time for a change?
Antibiotic therapy has been a successful alternative to surgery for more than 60 years, but surgery is still the primary treatment.
- Chronic anal pain: A review of causes, diagnosis, and treatment
The authors identify and review 3 main diagnostic categories: local causes, functional anorectal pain, and neuropathic pain syndromes.
- Esophageal adenocarcinoma: A dire need for early detection and treatment
A clinical overview focused on screening, multidisciplinary evaluation, and treatment of early esophageal adenocarcinoma.
- Oral hyperpigmentation with weakness and salt-craving
The patient’s primary care physician had attributed the hyperpigmentation on the lower lip and inner cheek to pen ink.
- Capsule endoscopy in gastrointestinal disease: Evaluation, diagnosis, and treatment
The procedure is mainly used to evaluate obscure bleeding in the small bowel, but it is also used in the evaluation and diagnosis of a wide range of gastrointestinal conditions.
- Hypercalcemia and vitamin A: A vitamin to keep in mind
Vitamin A toxicity can affect bone resorption and hypercalcemia and should be explored in unexplained cases of parathyroid hormone-independent hypercalcemia.
- Metronidazole-induced encephalopathy: Symmetrical hyperintensity on imaging
The diagnosis should be based on a combination of the patient’s clinical history, laboratory findings, and imaging results.
- Gastrointestinal varicella-zoster virus infection
Esophagogastroduodenoscopy showed small, shallow ulcers and erosions surrounded by red haloes, spread diffusely throughout the stomach and duodenum.

